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    首頁>>免疫學>>一抗>>CD27重組兔單克隆抗體  
    

    

    
	
    
    	
    
        	
    CD27重組兔單克隆抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN42161R
      
                        
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      中文名稱：
      
                            
      CD27重組兔單克隆抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-CD27 Monoclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
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      BN42161R-50ul
      
                                
      50ul
      
                                
      ￥2020.00
      
                                
      交叉反應：Mouse(predicted:Rat,Human)   推薦應用：WB,IHC-P,IHC-F,ICC
      
                            
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      BN42161R-100ul
      
                                
      100ul
      
                                
      ￥3240.00
      
                                
      交叉反應：Mouse(predicted:Rat,Human)   推薦應用：WB,IHC-P,IHC-F,ICC
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱CD27
    中文名稱CD27重組兔單克隆抗體
    別    名CD 27; Cd27; CD27 antigen; CD27 molecule; CD27_HUMAN; CD27L receptor; LPFS2; MGC20393; OTTHUMP00000238557; S152; T cell activation antigen CD27; T cell antivation antigen S152; T-cell activation antigen CD27; T14; TNFRSF 7; TNFRSF7; TNFSF7; Tp 55; Tp55; Tumor necrosis factor receptor superfamily member 7.  
    研究領域腫瘤  免疫學  干細胞  淋巴細胞  t-淋巴細胞  細胞因子  
    抗體來源Rabbit
    克隆類型Monoclonal
    克 隆 號3C3
    交叉反應Mouse,  (predicted: Human, Rat, )
    產品應用WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量55kDa
    細胞定位細胞膜 
    性    狀Lyophilized or Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CD27: 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMedPubMed
    產品介紹The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

    Function:
    Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

    Subunit:
    Homodimer. Interacts with SIVA1 and TRAF2.

    Subcellular Location:
    Membrane; Single-pass type I membrane protein.

    Tissue Specificity:
    Found in most T-lymphocytes.

    Post-translational modifications:
    Phosphorylated.
    O-glycosylated with core 1 or possibly core 8 glycans.

    Similarity:
    Contains 3 TNFR-Cys repeats.

    SWISS:
    P26842

    Gene ID:
    939

    Database links:
    Entrez Gene: 939 Human
    Entrez Gene: 21940 Mouse
    Entrez Gene: 500318 Rat
    Omim: 186711 Human
    SwissProt: P26842 Human
    SwissProt: P41272 Mouse
    Unigene: 355307 Human
    Unigene: 367714 Mouse
    Unigene: 134200 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.