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    首頁>>免疫學(xué)>>一抗>>組織相容性復(fù)合體蛋白1重組兔單克隆抗體
    組織相容性復(fù)合體蛋白1重組兔單克隆抗體
    • 產(chǎn)品貨號(hào):
      BN42146R
    • 中文名稱:
      組織相容性復(fù)合體蛋白1重組兔單克隆抗體
    • 英文名稱:
      Rabbit anti-MHC class I Monoclonal antibody
    • 品牌:
      Biorigin
    • 貨號(hào)

      產(chǎn)品規(guī)格

      售價(jià)

      備注

    • BN42146R-50ul

      50ul

      ¥2020.00

      交叉反應(yīng):Human 推薦應(yīng)用:WB,IHC-P

    • BN42146R-100ul

      100ul

      ¥3240.00

      交叉反應(yīng):Human 推薦應(yīng)用:WB,IHC-P

    產(chǎn)品描述

    英文名稱MHC class I
    中文名稱組織相容性復(fù)合體蛋白1重組兔單克隆抗體
    別    名MHC-1; MHC1; MHC 1; A 28; A 9; Aw 24; Aw 68; CLASS I HISTOCOMPATIBILITY ANTIGEN; H2 K1; H2K; HLA A; HLAA; HLA-A; HLA class I histocompatibility antigen A 1 alpha chain; HLA class I histocompatibility antigen A 11 alpha chain; HLA class I histocompatibility antigen A 2 alpha chain; HLA class I histocompatibility antigen A 24 alpha chain; HLA class I histocompatibility antigen A 3 alpha chain; HLA class I histocompatibility antigen A 30 alpha chain; HLA class I histocompatibility antigen A 32 alpha chain; HLA class I histocompatibility antigen A 68 alpha chain; Major histocompatibility complex class I A; MHC class I heavy chain H2 K; 1A24_HUMAN.  
    研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞分化  
    抗體來源Rabbit
    克隆類型Monoclonal
    克 隆 號(hào)10G4
    交叉反應(yīng)Human, 
    產(chǎn)品應(yīng)用WB=1:500-2000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量40kDa
    細(xì)胞定位細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human MHC class I: 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.

    Function:
    Involved in the presentation of foreign antigens to the immune system.

    Subunit:
    Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein (By similarity).

    Subcellular Location:
    Cell Membrane; Type I membrane protein.

    Post-translational modifications:
    Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).

    Similarity:
    Belongs to the MHC class I family.
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

    SWISS:
    P05534

    Gene ID:
    3105

    Database links:

    Entrez Gene: 3105 Human

    Omim: 142800 Human

    SwissProt: P30443 Human

    Unigene: 181244 Human 



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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