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    首頁(yè)>>免疫學(xué)>>一抗>>ADAM17重組兔單克隆抗體  
    

    

    
	
    
    	
    
        	
    ADAM17重組兔單克隆抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN42068R
      
                        
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      中文名稱：
      
                            
      ADAM17重組兔單克隆抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-ADAM17 (9E7) Monoclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
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      備注
      
                            
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      BN42068R-50ul
      
                                
      50ul
      
                                
      ￥2020.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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      BN42068R-100ul
      
                                
      100ul
      
                                
      ￥3240.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱ADAM17 (9E7)
    中文名稱ADAM17重組兔單克隆抗體
    別    名A disintegrin and metalloproteinase domain 17; ADAM 17; ADAM metallopeptidase domain 17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; MGC71942; Snake venom like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; Tumor Necrosis Factor Alpha Converting Enzyme; A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADA17_HUMAN.  
    研究領(lǐng)域腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
    抗體來(lái)源Rabbit
    克隆類型Monoclonal
    克 隆 號(hào)9E7
    交叉反應(yīng)Human, Mouse,  (predicted: Rat, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:20-200 IHC-F=1:20-200 ICC=1:20-200 IF=1:20-200 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量93kDa
    細(xì)胞定位細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原Recombinant human ADAM17 protein:700-824/824 <Cytoplasmic>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].

    Subunit:
    Interacts with MAD2L1, MAPK14 and MUC1.

    Subcellular Location:
    Membrane.

    Tissue Specificity:
    Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney.

    Similarity:
    Contains 1 disintegrin domain.
    Contains 1 peptidase M12B domain.

    SWISS:
    P78536

    Gene ID:
    6868

    Database links:
    Entrez Gene: 6868 Human
    Entrez Gene: 11491 Mouse
    Entrez Gene: 57027 Rat
    Omim: 603639 Human
    SwissProt: P78536 Human
    SwissProt: Q9Z0F8 Mouse
    SwissProt: Q9Z1K9 Rat
    Unigene: 404914 Human
    Unigene: 27681 Mouse
    Unigene: 144585 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.