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    首頁>>免疫學>>一抗>>細胞間粘附分子1抗體  
    

    

    
	
    
    	
    
        	
    細胞間粘附分子1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN41910R
      
                        
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      中文名稱：
      
                            
      細胞間粘附分子1抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-ICAM1 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      BN41910R-50ul
      
                                
      50ul
      
                                
      ￥1486.00
      
                                
      交叉反應：Human,Mouse(predicted:Rabbit)   推薦應用：WB,Flow-Cyt,ELISA
      
                            
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      BN41910R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse(predicted:Rabbit)   推薦應用：WB,Flow-Cyt,ELISA
      
                            
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      BN41910R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse(predicted:Rabbit)   推薦應用：WB,Flow-Cyt,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱ICAM1
    中文名稱細胞間粘附分子1抗體
    別    名BB2; CD54 antigen; CD54; ICAM1; ICAM 1; ICAM-1; Cell surface glycoprotein P3.58; Human rhinovirus receptor; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA2; MyD10; P3.58; Surface antigen of activated B cells; ICAM1_HUMAN; MALA-2; MyD10; intercellular adhesion molecule 1 precursor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor.  



    研究領域腫瘤  免疫學  信號轉導  干細胞  細胞粘附分子  細胞表面分子  糖蛋白  t-淋巴細胞  b-淋巴細胞  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1μg/Test 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量56kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CD54/ICAM-1:451-505/532 <Cytoplasmic>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008].

    Function:
    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

    Subunit:
    Homodimer (Probable). Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF. Binds to coxsackievirus A21 capsid proteins and acts as a receptor for this virus.

    Subcellular Location:
    Membrane; Single-pass type I membrane protein.

    Post-translational modifications:
    Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.

    Similarity:
    Belongs to the immunoglobulin superfamily. ICAM family.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.

    SWISS:
    P05362

    Gene ID:
    3383

    Database links:
    Entrez Gene: 3383 Human
    Entrez Gene: 15894 Mouse
    Entrez Gene: 25464 Rat
    Omim: 147840 Human
    Unigene: 643447 Human
    SwissProt: P05362 Human
    SwissProt: P13597 Mouse
    SwissProt: Q00238 Rat
    Unigene: 435508 Mouse
    Unigene: 12 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications