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    首頁(yè)>>免疫學(xué)>>一抗>>免疫球蛋白G Fc段受體I
    免疫球蛋白G Fc段受體I
    • 產(chǎn)品貨號(hào):
      BN41862R
    • 中文名稱:
      免疫球蛋白G Fc段受體I
    • 英文名稱:
      Rabbit anti-FCGR1A/CD64 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號(hào)

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    • BN41862R-50ul

      50ul

      ¥1486.00

      交叉反應(yīng):Human,Mouse,Rat 推薦應(yīng)用:WB,IHC-P,ICC,ELISA

    產(chǎn)品描述

    英文名稱FCGR1A/CD64
    中文名稱免疫球蛋白G Fc段受體I
    別    名CD 64; CD64 antigen; CD64A; Fc fragment of IgG high affinity Ia receptor; F Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc fragment of IgG, high affinity Ia, receptor for; Fc fragment of IgG, high affinity Ib, receptor (CD64); Fc fragment of IgG, high affinity Ib, receptor for; Fc fragment of IgG, high affinity Ic, receptor (CD64); Fc fragment of IgG, high affinity Ic, receptor for; Fc gamma receptor; Fc gamma receptor I A1; Fc gamma receptor I; Fc gamma receptor I B2; Fc gamma RI; Fc of IgG high affinity Ia receptor; Fc-gamma RIC; FCG 1; FCG1; FcgammaRI; FCGR 1; FCGR1; FCGR1A; FCGR1B; FCGR1C; FcRI; FCRIC; IGFR 1; IGFR1; IGFRB; IGFRC; IgG Fc receptor I; IgG Fc receptor IC; Immunoglobulin G Fc receptor I; Immunoglobulin G Fc receptor IB; Immunoglobulin G Fc receptor IC.  
    研究領(lǐng)域細(xì)胞生物  免疫學(xué)  細(xì)胞膜受體  細(xì)胞表面分子  
    抗體來(lái)源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse,  (predicted: Rat, Pig, Cow, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=1μg /test 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量41kDa
    細(xì)胞定位細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CD64/IGFR1:101-200/374 <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹The high affinity receptor for immunoglobulin G CD64 is encoded by a family of 3 genes that share over 98% of DNA sequence homology: FCGR1A, FCGR1B and FCGR1C. The FCGR1C gene, like FCGR1A, is located on 1q21. The third gene of this family, FCGR1B, was found at 1p12. CD64 plays a pivotal role in the immune response. It is a glycoprotein (MW 72 kD) that is constitutively expressed on human monocytes and macrophages.

    Subunit:
    Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL. Interacts with HCK and LYN.

    Subcellular Location:
    Cell membrane; Single-pass type I membrane protein. Note=Stabilized at the cell membrane through interaction with FCER1G.

    Tissue Specificity:
    Monocyte/macrophage specific.

    Similarity:
    Belongs to the immunoglobulin superfamily. FCGR1 family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

    SWISS:
    P12314

    Gene ID:
    2209

    Database links:

    Entrez Gene: 2209 Human

    Omim: 146760 Human

    SwissProt: P12314 Human

    Unigene: 77424 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    CD64是一種糖蛋白,主要定位于單核細(xì)胞和巨噬細(xì)胞,參與免疫應(yīng)答反應(yīng)。













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