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肌原調(diào)節(jié)蛋白抗體

產(chǎn)品貨號(hào)：

BN41822R
中文名稱：

肌原調(diào)節(jié)蛋白抗體
英文名稱：

Rabbit anti-MyoD1/Myf3 Polyclonal antibody
品牌：

Biorigin

貨號(hào)

產(chǎn)品規(guī)格

售價(jià)

備注
BN41822R-50ul

50ul

￥1486.00

交叉反應(yīng)：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep) 推薦應(yīng)用：WB,ELISA
BN41822R-100ul

100ul

￥2360.00

交叉反應(yīng)：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep) 推薦應(yīng)用：WB,ELISA
BN41822R-200ul

200ul

￥3490.00

交叉反應(yīng)：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep) 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱	MyoD1/Myf3
中文名稱	肌原調(diào)節(jié)蛋白抗體
別名	Myogenic differentiation 1; AI503393; bHLHc1; MD1; MGC156574; MYF3; MYOD; MYOD1; PUM; MYOD1_HUMAN; Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3

研究領(lǐng)域	免疫學(xué) 發(fā)育生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應(yīng)	Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	35kDa
細(xì)胞定位	細(xì)胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from mouse MyoD1:51-150/318
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008] Function: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins. Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Seems to form active heterodimers with ITF-2. Interacts with SUV39H1 and CDK9. Interacts with DDX5. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated by CDK9. This phosphorylation promotes its function in muscle differentiation. Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function. Ubiquitinated on the N-terminus; which is required for proteasomal degradation Similarity: Contains 1 bHLH (basic helix-loop-helix) domain. SWISS: P10085 Gene ID: 17927 Database links: Entrez Gene: 374048 Chicken Entrez Gene: 281938 Cow Entrez Gene: 4654 Human Entrez Gene: 17927 Mouse Entrez Gene: 407604 Pig Entrez Gene: 337868 Rat Entrez Gene: 443405 Sheep Omim: 159970 Human SwissProt: P16075 Chicken SwissProt: Q7YS82 Cow SwissProt: P15172 Human SwissProt: P10085 Mouse SwissProt: P49811 Pig SwissProt: Q02346 Rat SwissProt: P29331 Sheep Unigene: 181768 Human Unigene: 1526 Mouse Unigene: 9493 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.