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    首頁>>免疫學>>一抗>>細胞衰老抑制基因抗體  
    

    

    
	
    
    	
    
        	
    細胞衰老抑制基因抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN41805R
      
                        
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      中文名稱：
      
                            
      細胞衰老抑制基因抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-RSL1D1 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      BN41805R-50ul
      
                                
      50ul
      
                                
      ￥1486.00
      
                                
      交叉反應：Mouse,Rat   推薦應用：WB,IHC-P
      
                            
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      BN41805R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Mouse,Rat   推薦應用：WB,IHC-P
      
                            
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      BN41805R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Mouse,Rat   推薦應用：WB,IHC-P
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱RSL1D1
    中文名稱細胞衰老抑制基因抗體
    別    名CATX 11; CATX-11; CATX11; Cellular senescence inhibited gene protein; L12; PBK1; CSIG; L12; PBK1; Protein PBK1; Ribosomal L1 domain-containing protein 1; RL1D1_HUMAN; Ribosomal L1 domain containing 1.  
    研究領域腫瘤  染色質和核信號  信號轉導  細胞周期蛋白  轉錄調節因子  細胞分化  表觀遺傳學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat, 
    產品應用WB=1:500-2000 IHC-P=1:400-800 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量55kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from mouse RSL1D1:311-410/452 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹RSL1D1, also known as CATX-11, PBK1, L12 or CSIG, is a 490 amino acid nuclear protein that belongs to the ribosomal protein L1P family. Expressed in placenta, RSL1D1 contains many phosphorylated amino acid residues and is encoded by a gene that maps to human chromosome 16p13.13. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias.

    Subcellular Location:
    Nucleus, nucleolus.

    Tissue Specificity:
    Placenta.

    Similarity:
    Belongs to the ribosomal protein L1P family. Highly divergent.

    SWISS:
    Q8BVY0

    Gene ID:
    66409

    Database links:
    Entrez Gene: 26156 Human
    SwissProt: O76021 Human
    Unigene: 401842 Human


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    CSIG可抑制細胞衰老并延長細胞壽命 ,可能通過核糖體生物合成過程或基因轉錄調節來調控細胞衰老過程.