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    首頁>>免疫學(xué)>>一抗>>鈉鈣交換蛋白1抗體
    鈉鈣交換蛋白1抗體
    • 產(chǎn)品貨號:
      BN41729R
    • 中文名稱:
      鈉鈣交換蛋白1抗體
    • 英文名稱:
      Rabbit anti-NCX1 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產(chǎn)品規(guī)格

      售價

      備注

    • BN41729R-50ul

      50ul

      ¥1486.00

      交叉反應(yīng):Human,Mouse,Rat,GuineaPig(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    • BN41729R-100ul

      100ul

      ¥2360.00

      交叉反應(yīng):Human,Mouse,Rat,GuineaPig(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    • BN41729R-200ul

      200ul

      ¥3490.00

      交叉反應(yīng):Human,Mouse,Rat,GuineaPig(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

    產(chǎn)品描述

    英文名稱NCX1
    中文名稱鈉鈣交換蛋白1抗體
    別    名Na+/Ca2+exchanger 1; CNC; DKFZp779F0871; MGC119581; FLJ37694; FLJ43417; Na+/Ca2+ exchange protein 1; Na+/Ca2+ exchanger; NCX 1; NCX; SLC8A1; SLC8A1 protein; Sodium Calcium Exchanger; Sodium/calcium exchanger 1; Solute carrier family 8 member 1; NAC1_HUMAN.  



    研究領(lǐng)域腫瘤  免疫學(xué)  轉(zhuǎn)運蛋白  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/test IF=1:100-500 (石蠟切片需做抗原修復(fù))
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量106kDa
    細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human NCX1:801-900/971 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma(plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM].

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Expressed in cardiac sarcolemma, brain, kidney, liver, pancreas, skeletal muscle, placenta and lung.

    Similarity:
    Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily. Contains 2 Calx-beta domains.

    SWISS:
    P32418

    Gene ID:
    6546

    Database links:

    Entrez Gene: 6546 Human

    Entrez Gene: 20541 Mouse

    Entrez Gene: 100328570 Rabbit

    Entrez Gene: 29715 Rat

    Omim: 182305 Human

    SwissProt: P23685 Dog

    SwissProt: P48766 Guinea pig

    SwissProt: P32418 Human

    SwissProt: P70414 Mouse

    SwissProt: Q01728 Rat

    Unigene: 31961 Human

    Unigene: 468274 Human

    Unigene: 728911 Human

    Unigene: 265834 Mouse

    Unigene: 118972 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.