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    首頁>>免疫學>>一抗>>緊密連接蛋白抗體  
    

    

    
	
    
    	
    
        	
    緊密連接蛋白抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號：
      
                            
      BN41722R
      
                        
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      中文名稱：
      
                            
      緊密連接蛋白抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-OCLN Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價
      
                                
      備注
      
                            
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      BN41722R-50ul
      
                                
      50ul
      
                                
      ￥1486.00
      
                                
      交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,GuineaPig)   推薦應用：WB,Flow-Cyt,ELISA
      
                            
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      BN41722R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,GuineaPig)   推薦應用：WB,Flow-Cyt,ELISA
      
                            
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      BN41722R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,GuineaPig)   推薦應用：WB,Flow-Cyt,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱OCLN
    中文名稱緊密連接蛋白抗體
    別    名Occludin, Occludin-1; Occludin1; Occludin 1; FLJ08163; BLCPMG; FLJ18079; FLJ77961; FLJ94056; MGC34277; Occludin; OCLN; OCLN_HUMAN; Tight junction protein occludin.   

    研究領域細胞生物  免疫學  轉錄調節(jié)因子  細胞粘附分子  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig, )
    產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=2μg/Test 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量57kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from mouse OCLN:431-522/522 <Cytoplasmic>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described. [provided by RefSeq].

    Function:
    May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.

    Subunit:
    Interacts with TJP1/ZO1 and with VAPA.

    Subcellular Location:
    Membrane; Multi-pass membrane protein. Cell junction, tight junction.

    Tissue Specificity:
    Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis.

    Post-translational modifications:
    Phosphorylated upon DNA damage, probably by ATM or ATR. Dephosphorylated by PTPRJ. May be phosphorylated by PKC during translocation to cell-cell contacts.

    Similarity:
    Belongs to the ELL/occludin family.
    Contains 1 MARVEL domain.

    SWISS:
    Q61146

    Gene ID:
    18260

    Database links:
    Entrez Gene: 18260 Mouse
    Entrez Gene: 100506658 Human
    Entrez Gene: 397236 Pig
    Entrez Gene: 83497 Rat
    Entrez Gene: 403844 Dog
    Omim: 602876 Human
    SwissProt: Q28269 Dog
    SwissProt: Q16625 Human
    SwissProt: Q61146 Mouse
    SwissProt: Q6P6T5 Rat
    Unigene: 592605 Human
    Unigene: 4807 Mouse
    Unigene: 31429 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.