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    最近搜索：細胞培養 微生物學 分子生物 生物化學 
    

    

    
	
    首頁>>免疫學>>一抗>>早期生長應答蛋白1抗體  
    

    

    
	
    
    	
    
        	
    早期生長應答蛋白1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN41648R
      
                        
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      中文名稱：
      
                            
      早期生長應答蛋白1抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-Egr1 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      BN41648R-50ul
      
                                
      50ul
      
                                
      ￥1486.00
      
                                
      交叉反應：Human,Mouse,Rat   推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
      
                            
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      BN41648R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse,Rat   推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
      
                            
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      BN41648R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse,Rat   推薦應用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱Egr1
    中文名稱早期生長應答蛋白1抗體
    別    名Egr-1; Early growth response 1; Krox-24; Ngf1; Ngfi; NGFI-A; zif-268; Egr1; A530045N19Rik; egr; Egr-1; ETR103; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; AT 225; AT225; Early growth response protein 1; G0S 30; G0S30; KROX 24; Krox 24 protein; KROX24; TIS 8; TIS8; Transcription factor ETR 103; Transcription factor ETR103; Transcription factor Zif 268; Transcription factor Zif268; Zfp 6; ZIF268; Zinc finger protein 225; ZNF 225; ZNF225; EGR1_HUMAN.  
    研究領域細胞生物  免疫學  信號轉導  生長因子和激素  細胞周期蛋白  轉錄調節因子  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat, 
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=0.2ug/test IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量60kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Egr-1:401-500/453 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. [provided by RefSeq].

    Function:
    Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.

    Subcellular Location:
    Nucleus.

    Similarity:
    Belongs to the EGR C2H2-type zinc-finger protein family.
    Contains 3 C2H2-type zinc fingers.

    SWISS:
    P18146

    Gene ID:
    1958

    Database links:
    Entrez Gene: 1958 Human
    Entrez Gene: 13653 Mouse
    Omim: 128990 Human
    SwissProt: P18146 Human
    SwissProt: P08046 Mouse
    Unigene: 326035 Human
    Unigene: 708393 Human
    Unigene: 181959 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    Egr-1為即刻早期基因家族中的一個成員,是一種含3個鋅指結構的轉錄因子。有研究表明EGR-1在細胞生長分化中發揮重要作用，如在細胞周期G1-S期的轉換過程中Egr-1被誘導表達。