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    首頁(yè)>>免疫學(xué)>>一抗>>神經(jīng)元特異性烯醇化酶/γ 烯醇化酶抗體  
    

    

    
	
    
    	
    
        	
    神經(jīng)元特異性烯醇化酶/γ 烯醇化酶抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN41629R
      
                        
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      中文名稱(chēng)：
      
                            
      神經(jīng)元特異性烯醇化酶/γ 烯醇化酶抗體 
      
                        
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      英文名稱(chēng)：
      
                            
      Rabbit anti-NSE Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
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      BN41629R-50ul
      
                                
      50ul
      
                                
      ￥1486.00
      
                                
      交叉反應(yīng)：Dog,Rat,Mouse,Human(predicted:Cow,Chicken)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
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      BN41629R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Dog,Rat,Mouse,Human(predicted:Cow,Chicken)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
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      BN41629R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Dog,Rat,Mouse,Human(predicted:Cow,Chicken)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱(chēng)NSE
    中文名稱(chēng)神經(jīng)元特異性烯醇化酶/γ 烯醇化酶抗體
    別    名Gamma-enolase; Gamma enolase; Neural enolase; Neuron specific enolase; neurone-specific enolase; 2 phospho D glycerate hydrolyase; Eno 2; Eno2; ENO2; ENOG; Enolase 2; Enolase 2 gamma neuronal; Enolase2; Neuron specific enolase; Neuron specific gamma enolase; NSE; ENOG_HUMAN; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; enolase 2, gamma, neuronal.  


    研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  腫瘤細(xì)胞生物標(biāo)志物  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應(yīng)Human, Mouse, Rat, Dog,  (predicted: Chicken, Cow, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test  IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量48kDa
    細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human NSE:201-300/434 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008].

    Function:
    Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.

    Subunit:
    Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific.

    Subcellular Location:
    Cytoplasm. Cell membrane. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.

    Tissue Specificity:
    The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.

    Similarity:
    Belongs to the enolase family.

    SWISS:
    P09104

    Gene ID:
    2026

    Database links:
    Entrez Gene: 2026 Human
    Entrez Gene: 13807 Mouse
    Entrez Gene: 24334 Rat
    Omim: 131360 Human
    SwissProt: P09104 Human
    SwissProt: P17183 Mouse
    SwissProt: P07323 Rat
    Unigene: 511915 Human


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    神經(jīng)元特異性烯醇化酶（NSE）存在于神經(jīng)元細(xì)胞和神經(jīng)內(nèi)分泌組織中，起源于神經(jīng)內(nèi)分泌細(xì)胞的腫瘤可產(chǎn)生過(guò)量的NSE。NSE也是小細(xì)胞肺癌的檢測(cè)指標(biāo)，70％左右的小細(xì)胞肺癌患者血中NSE升高，而其他組織型肺癌NSE升高的患者僅為10％～20％。