<strike id="amuic"></strike>
  • <abbr id="amuic"><option id="amuic"></option></abbr>
    <strike id="amuic"></strike>
    

  • <cite id="amuic"><source id="amuic"></source></cite>

    <cite id="amuic"><source id="amuic"></source></cite>
    • <ul id="amuic"><table id="amuic"></table></ul>
    


    
    
    
        
        
    
    
    

    

    
    
    
    
    
        
        
    
    
        
    

    

    
    
    
    
    
        
        
    
    
    
    最近搜索：細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué) 
    

    

    
	
    首頁(yè)>>免疫學(xué)>>一抗>>多巴胺受體D1抗體  
    

    

    
	
    
    	
    
        	
    多巴胺受體D1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
    • 
                        	
      產(chǎn)品貨號(hào)：
      
                            
      BN41614R
      
                        
      • 
                    	
    • 
                        	
      中文名稱：
      
                            
      多巴胺受體D1抗體 
      
                        
      • 
                                            	
    • 
                        	
      英文名稱：
      
                            
      Rabbit anti-Dopamine Receptor D1 Polyclonal antibody 
      
                        
      • 
                                                                    	
    • 
                        	
      品牌：
      
                            
      Biorigin 
      
                        
      • 
                    
    
                
    
            
    
            
    
                    
    
                        
      
                            
    • 
                                
      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
      • 
                                                        
    • 
                                
      BN41614R-50ul
      
                                
      50ul
      
                                
      ￥1486.00
      
                                
      交叉反應(yīng)：Human,Mouse,Rat   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
      • 
                                                        
    • 
                                
      BN41614R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Human,Mouse,Rat   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
      • 
                                                        
    • 
                                
      BN41614R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Human,Mouse,Rat   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
      • 
                                                    
    
                    
    
              
    
            
    
            	
    
                	
    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱Dopamine Receptor D1
    中文名稱多巴胺受體D1抗體
    別    名DRD1; dopamine D1 receptor; D(1A) dopamine receptor; D1A dopamine receptor; Dopamine D1Receptors; D1DR; DADR; Dopamine Receptor D1; DR D1; DR D1A; DRD 1; DRD1 receptor; DRD1; DRD1A; DRD1_HUMAN; D(1A) dopamine receptor; DRD 1A; DRD1.  


    研究領(lǐng)域腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  
    抗體來(lái)源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse, Rat, 
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量50kDa
    細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human DRD1:101-200/446 <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]

    Function:
    Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

    Subunit:
    Interacts with DNAJC14 via its C-terminus. Interacts with DRD1IP.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Detected in caudate, nucleus accumbens and in the olfactory tubercle.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    SWISS:
    P21728

    Gene ID:
    1812

    Database links:
    Entrez Gene: 1812 Human
    Entrez Gene: 13488 Mouse
    Entrez Gene: 24316 Rat
    Omim: 126449 Human
    SwissProt: P21728 Human
    SwissProt: Q61616 Mouse
    SwissProt: P18901 Rat
    Unigene: 2624 Human
    Unigene: 54161 Mouse
    Unigene: 24039 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    多巴胺受體D1在運(yùn)動(dòng)協(xié)調(diào)方面起重要作用，該受體的缺失對(duì)黑質(zhì)多巴胺能神經(jīng)元的影響程度雖沒(méi)臨床帕金森病（PD）嚴(yán)重，但仍可加速多巴胺能神經(jīng)元發(fā)生退行性改變.該蛋白目前主要用于神經(jīng)退行性改變的研究。