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    首頁>>免疫學>>一抗>>骨鈣蛋白/骨鈣素抗體  
    

    

    
	
    
    	
    
        	
    骨鈣蛋白/骨鈣素抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN41538R
      
                        
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      中文名稱：
      
                            
      骨鈣蛋白/骨鈣素抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-Osteocalcin Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      BN41538R-50ul
      
                                
      50ul
      
                                
      ￥1486.00
      
                                
      交叉反應：Human,Mouse(predicted:Rat,Dog,Cow,Horse)   推薦應用：IHC-P,IHC-F,IF,ELISA
      
                            
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      BN41538R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse(predicted:Rat,Dog,Cow,Horse)   推薦應用：IHC-P,IHC-F,IF,ELISA
      
                            
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      BN41538R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse(predicted:Rat,Dog,Cow,Horse)   推薦應用：IHC-P,IHC-F,IF,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱Osteocalcin
    中文名稱骨鈣蛋白/骨鈣素抗體
    別    名Osteocalcin Propeptide; Osteocalcin; Osteocalcin precursor; Gamma-carboxyglutamic acid-containing protein; Bone Gla-protein; BGLAP; Bone gamma carboxyglutamate protein; BGLAP; BGP; Bone gamma carboxyglutamate gla protein osteocalcin; Bone gamma carboxyglutamate protein; Bone Gla protein; Gamma carboxyglutamic acid containing protein; OC; PMF1; OSTCN_HUMAN.  


    研究領域免疫學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, Dog, Cow, Horse, )
    產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量11kDa
    細胞定位分泌型蛋白 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human BGP:21-80/100 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.

    Function:
    Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.

    Subcellular Location:
    Secreted.

    Post-translational modifications:
    Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.

    Similarity:
    Belongs to the osteocalcin/matrix Gla protein family.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.

    SWISS:
    P02818

    Gene ID:
    632

    Database links:
    Entrez Gene: 281646 Cow
    Entrez Gene: 632 Human
    Entrez Gene: 397530 Pig
    Entrez Gene: 25295 Rat
    Omim: 112260 Human
    SwissProt: P02820 Cow
    SwissProt: P02818 Human
    SwissProt: Q8HYY9 Pig
    SwissProt: P04640 Rat
    Unigene: 654541 Human
    Unigene: 9722 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    骨鈣素又稱骨γ-羧谷氨酸包含蛋白