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    首頁>>免疫學(xué)>>一抗>>鈣結(jié)合蛋白抗體  
    

    

    
	
    
    	
    
        	
    鈣結(jié)合蛋白抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN41476R
      
                        
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      中文名稱：
      
                            
      鈣結(jié)合蛋白抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-Calretinin Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
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      BN41476R-50ul
      
                                
      50ul
      
                                
      ￥1486.00
      
                                
      交叉反應(yīng)：Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
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      BN41476R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
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      BN41476R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Rat,Human(predicted:Horse,Cow,Pig,Dog,Mouse)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱Calretinin
    中文名稱鈣結(jié)合蛋白抗體
    別    名29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; CR; CALB2_HUMAN; Calretinin.  
    研究領(lǐng)域神經(jīng)生物學(xué)  結(jié)合蛋白  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量29kDa
    細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Calretinin:211-271/271 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Calretinin is a calcium-binding protein which is abundant in auditory neurons. It belongs to the calbindin family. Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin1.

    Function:
    Calretinin is a calcium-binding protein which is abundant in auditory neurons.

    Tissue Specificity:
    Brain.

    Similarity:
    Belongs to the calbindin family.
    Contains 6 EF-hand domains.

    SWISS:
    P22676

    Gene ID:
    794

    Database links:
    Entrez Gene: 396255 Chicken
    Entrez Gene: 794 Human
    Entrez Gene: 12308 Mouse
    Entrez Gene: 117059 Rat
    Entrez Gene: 393684 Zebrafish
    Omim: 114051 Human
    SwissProt: P07090 Chicken
    SwissProt: P22676 Human
    SwissProt: Q08331 Mouse
    SwissProt: P47728 Rat
    Unigene: 106857 Human
    Unigene: 2755 Mouse
    Unigene: 10321 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


    鈣結(jié)合蛋白(Calretinin,CR)主要存在于神經(jīng)組織中，近10%的腺癌可以表達(dá)此蛋白的局部染色陽性，而絕大多數(shù)的間皮瘤為陽性表達(dá)，因此它是診斷間皮瘤的一個(gè)有用的標(biāo)記物 。
    鈣結(jié)合蛋白是平滑肌和非肌性調(diào)控蛋白。它可以與肌動(dòng)蛋白、肌球蛋白、原肌球蛋白和鈣調(diào)素相互作用。