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    首頁>>免疫學>>一抗>>溶質載體蛋白家族47成員A1抗體  
    

    

    
	
    
    	
    
        	
    溶質載體蛋白家族47成員A1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN41376R
      
                        
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      中文名稱：
      
                            
      溶質載體蛋白家族47成員A1抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-SLC47A1 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      BN41376R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Cow,Horse,Rabbit,Sheep)   推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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      BN41376R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Cow,Horse,Rabbit,Sheep)   推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱SLC47A1
    中文名稱溶質載體蛋白家族47成員A1抗體
    別    名1A1; AIM 1; AIM1; MATP; Melanoma antigen AIM1; Membrane associated transporter; Membrane associated transporter protein; Membrane-associated transporter protein; Protein AIM 1; Protein AIM-1; Protein AIM1; S45A2_HUMAN; SHEP5; SLC45A2; Solute carrier family 45 member 2; Underwhite.  
    研究領域腫瘤  細胞生物  信號轉導  細胞膜蛋白  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Cow, Horse, Rabbit, Sheep, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量58kDa
    細胞定位細胞漿 細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human SLC47A1:211-310/530 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

    Function:
    Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.

    Subcellular Location:
    Cell membrane. Predominantly localized at the plasma membrane but also found in intracellular organelles.

    Tissue Specificity:
    Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes).

    Similarity:
    Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.

    SWISS:
    Q96FL8

    Gene ID:
    55244

    Database links:
    Entrez Gene: 55244 Human
    Omim: 609832 Human
    SwissProt: Q96FL8 Human
    Unigene: 232054 Human


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.