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    首頁>>免疫學>>一抗>>葡萄糖神經酰胺合成酶抗體  
    

    

    
	
    
    	
    
        	
    葡萄糖神經酰胺合成酶抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN41340R
      
                        
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      中文名稱：
      
                            
      葡萄糖神經酰胺合成酶抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-Ceramide glucosyltransferase  Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
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      BN41340R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)   推薦應用：WB,IHC-P,ELISA
      
                            
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      BN41340R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)   推薦應用：WB,IHC-P,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱Ceramide glucosyltransferase
    中文名稱葡萄糖神經酰胺合成酶抗體
    別    名CEGT_HUMAN; UGCG; GCS; GLCT 1; GLCT-1; GLCT1; Glucosylceramide synthase; UDP glucose ceramide glucosyltransferase; UDP glucose N acylsphingosine D glucosyltransferase; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; Ugcg.  
    研究領域腫瘤  細胞生物  細胞凋亡  細胞分化  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量45kDa
    細胞定位細胞漿 細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human UGCG:31-98/394 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Glucosylceramide synthase (GCS), also designated ceramide glucosyltransferase, belongs to the glycosyltransferase 2 family. It is a widely expressed integral membrane protein encoded by UGCG. The enzyme can be found in the plasma membrane of all eukaryotic cells, and a significant concentration of glucosylceramide synthase activity has been reported in the Golgi complex. Glucosylceramide synthase catalyzes the first glycosylation step in glycosphingolipid biosynthesis and functions as a glucosyltransferase and flippase in the transfer of glucose to ceramide. Glucosylceramide synthase operates in cell recognition, cell proliferation and differentiation, immune recognition and signal transduction. The regulation of ceramide levels through glucosylceramide synthase has been associated with the induction of apoptosis and notable research implicates this relationship with drug-induced apoptosis in a variety of cell types.

    Function:
    Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".

    Subcellular Location:
    Golgi apparatus membrane.

    Tissue Specificity:
    Found in all tissues examined.

    Similarity:
    Belongs to the glycosyltransferase 2 family.

    SWISS:
    Q16739

    Gene ID:
    7357

    Database links:
    Entrez Gene: 7357 Human
    Entrez Gene: 22234 Mouse
    Entrez Gene: 83626 Rat
    Omim: 602874 Human
    SwissProt: Q16739 Human
    SwissProt: O88693 Mouse
    SwissProt: Q9R0E0 Rat
    Unigene: 304249 Human
    Unigene: 593014 Human
    Unigene: 198803 Mouse
    Unigene: 24091 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.