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    首頁>>免疫學(xué)>>一抗>>Irx3蛋白抗體  
    

    

    
	
    
    	
    
        	
    Irx3蛋白抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN41280R
      
                        
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      中文名稱：
      
                            
      Irx3蛋白抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-Iroquois homeobox protein 3 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
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      BN41280R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Pig,Cow)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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      BN41280R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Pig,Cow)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱Iroquois homeobox protein 3
    中文名稱Irx3蛋白抗體
    別    名IRXB1; Homeodomain protein IRXB1; Iroquois homeobox protein 3; Iroquois-class homeodomain protein IRX-3; IRX 1; Irx3; IRX3_HUMAN; AI894186.  
    研究領(lǐng)域細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞周期蛋白  細(xì)胞分化  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量52kDa
    細(xì)胞定位細(xì)胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Iroquois homeobox protein 3:401-501/501 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells.

    Function:
    Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).

    Subunit:
    Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.

    Subcellular Location:
    Nucleus.

    Similarity:
    Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.

    SWISS:
    P78415

    Gene ID:
    79191

    Database links:
    UniProtKB/Swiss-Prot: P78415.3
    Entrez Gene: 79191 Human
    Entrez Gene: 16373 Mouse
    Omim: 612985 Human
    SwissProt: P78415 Human
    SwissProt: P81067 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.