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    首頁>>免疫學(xué)>>一抗>>絲氨酸/蘇氨酸蛋白激酶3抗體  
    

    

    
	
    
    	
    
        	
    絲氨酸/蘇氨酸蛋白激酶3抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號：
      
                            
      BN41259R
      
                        
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      中文名稱：
      
                            
      絲氨酸/蘇氨酸蛋白激酶3抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-MST3/STK3 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
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      BN41259R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Dog,Chicken)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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      BN41259R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Dog,Chicken)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱MST3/STK3
    中文名稱絲氨酸/蘇氨酸蛋白激酶3抗體
    別    名Kinase responsive to stress 1; KRS1; Mammalian STE20 like protein kinase 2; Mammalian sterile 20-like 2; Mess1; MST; MST-2; MST2; Mst3; Serine/threonine kinase 3 (STE20 homolog, yeast); Serine/threonine kinase 3 (Ste20, yeast homolog); Serine/threonine protein kinase 3; Serine/threonine protein kinase Krs1; STE20 like kinase MST2.  


    研究領(lǐng)域細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Mouse,  (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量56kDa
    細(xì)胞定位細(xì)胞核 細(xì)胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human STK3:101-200/491 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹STK3 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation.

    Subunit:
    Homodimer; mediated via the coiled-coil region. Interacts with NORE1, which inhibits autoactivation. Interacts with and stabilizes SAV1. Interacts with RAF1, which prevents dimerization and phosphorylation. Interacts with RASSF1. Interacts (via SARAH domain) with isoform 1 of NEK2. Interacts with ESR1 only in the presence of SAV1. Interacts with PKB/AKT1. Forms a tripartite complex with MOBKL1B and STK38. Interacts with RASSF2 (via SARAH domain).

    Subcellular Location:
    Cytoplasm. Nucleus.

    Tissue Specificity:
    Expressed at high levels in adult kidney, skeletal and placenta tissues and at very low levels in adult heart, lung and brain tissues.

    Similarity:
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SARAH domain.

    SWISS:
    Q9Y6E0

    Gene ID:
    8428

    Database links:
    Entrez Gene: 8428 Human
    Entrez Gene: 223255 Mouse
    Entrez Gene: 361092 Rat
    Omim: 604984 Human
    SwissProt: Q9Y6E0 Human
    SwissProt: Q99KH8 Mouse
    SwissProt: B0LT89 Rat
    Unigene: 508514 Human
    Unigene: 390756 Mouse
    Unigene: 442081 Mouse
    Unigene: 472866 Mouse
    Unigene: 105397 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.