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    首頁>>免疫學(xué)>>一抗>>肌萎縮相關(guān)蛋白1抗體  
    

    

    
	
    
    	
    
        	
    肌萎縮相關(guān)蛋白1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號：
      
                            
      BN41245R
      
                        
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      中文名稱：
      
                            
      肌萎縮相關(guān)蛋白1抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-RERE Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價
      
                                
      備注
      
                            
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      BN41245R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse)   推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA
      
                            
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      BN41245R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat,Chicken,Dog,Cow,Horse)   推薦應(yīng)用：IHC-P,IHC-F,IF,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱RERE
    中文名稱肌萎縮相關(guān)蛋白1抗體
    別    名ARG; arginine glutamic acid dipeptide (RE) repeats; arginine glutamic acid dipeptide repeats; Arginine glutamic acid dipeptide repeats protein; Arginine-glutamic acid dipeptide repeats protein; ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE; ARP; ATN1L; Atr2; atrophin 1 like; Atrophin 1 like protein; Atrophin 1 related protein; atrophin 2; atrophin related protein; ATROPHIN-1-ASSOCIATED PROTEIN; Atrophin-1-like protein; Atrophin-1-related protein; atrophin-2; ATROPHIN-RELATED PROTEIN; DNB1; Rere; RERE_HUMAN.  
    研究領(lǐng)域細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse,  (predicted: Rat, Chicken, Dog, Cow, Horse, )
    產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量172kDa
    細(xì)胞定位細(xì)胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human RERE:521-620/1566 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹FunctionPlays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

    Function:
    Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.

    Subunit:
    Interacts with HDAC1 (By similarity). Interacts with ATN1. Interaction with ATN1 is improved when the poly-Gln region of ATN1 is extended. Interacts with FAT1.

    Subcellular Location:
    Nucleus. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.

    Tissue Specificity:
    Widely expressed. Expressed in tumor cell lines.

    DISEASE:
    Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24).

    Similarity:
    Contains 1 BAH domain.
    Contains 1 ELM2 domain.
    Contains 1 GATA-type zinc finger.
    Contains 1 SANT domain.

    SWISS:
    Q9P2R6

    Gene ID:
    473

    Database links:
    UniProtKB/Swiss-Prot: Q9P2R6.2

    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.















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