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    首頁(yè)>>免疫學(xué)>>一抗>>內(nèi)質(zhì)網(wǎng)核信號(hào)轉(zhuǎn)導(dǎo)蛋白2抗體  
    

    

    
	
    
    	
    
        	
    內(nèi)質(zhì)網(wǎng)核信號(hào)轉(zhuǎn)導(dǎo)蛋白2抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN41233R
      
                        
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      中文名稱：
      
                            
      內(nèi)質(zhì)網(wǎng)核信號(hào)轉(zhuǎn)導(dǎo)蛋白2抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-ERN2 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
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      BN41233R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep)   推薦應(yīng)用：Flow-Cyt,ELISA
      
                            
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      BN41233R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep)   推薦應(yīng)用：Flow-Cyt,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱ERN2
    中文名稱內(nèi)質(zhì)網(wǎng)核信號(hào)轉(zhuǎn)導(dǎo)蛋白2抗體
    別    名IRE1b; Endoplasmic reticulum to nucleus signaling 2; ER to nucleus signalling 2; ERN 2; Ern1; hIRE2p; Inositol requiring 1 beta; Inositol requiring protein 2; Ire1; Ire1 beta; IRE1 S. cerevisiae homolog of; IRE2; Serine/threonine protein kinase/endoribonuclease IRE2; ERN2_HUMAN.  
    研究領(lǐng)域細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  表觀遺傳學(xué)  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應(yīng)Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Sheep, )
    產(chǎn)品應(yīng)用ELISA=1:5000-10000 Flow-Cyt=2ug/Test 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量98kDa
    細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human ERN2:465-550/926 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins.

    Function:
    Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.

    Subcellular Location:
    Endoplasmic reticulum membrane; Single-pass type I membrane protein.

    Post-translational modifications:
    Autophosphorylated.

    Similarity:
    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    Contains 1 KEN domain.
    Contains 1 protein kinase domain.

    SWISS:
    O75460

    Gene ID:
    10595

    Database links:
    Entrez Gene: 10595 Human
    Entrez Gene: 26918 Mouse
    Omim: 604034 Human
    SwissProt: O75460 Human
    SwissProt: Q9EQY0 Mouse
    Unigene: 133982 Human
    Unigene: 20452 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.










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