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    首頁>>免疫學>>一抗>>上游結合蛋白1抗體  
    

    

    
	
    
    	
    
        	
    上游結合蛋白1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN41230R
      
                        
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      中文名稱：
      
                            
      上游結合蛋白1抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-Upstream Binding Protein 1 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      備注
      
                            
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      BN41230R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse)   推薦應用：WB,ELISA
      
                            
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      BN41230R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse)   推薦應用：WB,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱Upstream Binding Protein 1
    中文名稱上游結合蛋白1抗體
    別    名LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.  
    研究領域腫瘤  細胞生物  信號轉導  轉錄調節因子  結合蛋白  表觀遺傳學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量60kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1:351-450/540 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

    Function:
    UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.

    Subunit:
    Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.

    Similarity:
    Belongs to the grh/CP2 family. CP2 subfamily.

    SWISS:
    Q9NZI7

    Gene ID:
    7342

    Database links:
    Entrez Gene: 7342 Human
    Entrez Gene: 22221 Mouse
    Entrez Gene: 301038 Rat
    Omim: 609784 Human
    SwissProt: Q86Y57 Human
    SwissProt: Q9NZI7 Human
    SwissProt: Q60786 Mouse
    SwissProt: Q811S7 Mouse
    SwissProt: Q8BH21 Mouse
    Unigene: 118041 Human
    Unigene: 729120 Human
    Unigene: 28052 Mouse
    Unigene: 386808 Mouse
    Unigene: 15705 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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