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    首頁(yè)>>免疫學(xué)>>一抗>>鋅指蛋白379抗體  
    

    

    
	
    
    	
    
        	
    鋅指蛋白379抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN41198R
      
                        
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      中文名稱：
      
                            
      鋅指蛋白379抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-ZNF379 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
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      BN41198R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit)   推薦應(yīng)用：WB
      
                            
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      BN41198R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit)   推薦應(yīng)用：WB
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱ZNF379
    中文名稱鋅指蛋白379抗體
    別    名CXorf11; DHHC9; Palmitoyltransferase ZDHHC9; ZDHHC 9; ZDHHC10; Zinc finger DHHC domain containing protein 9; Zinc finger protein 379; ZNF379; ZNF380; ZDHC9_HUMAN.  
    研究領(lǐng)域腫瘤  信號(hào)轉(zhuǎn)導(dǎo)  腫瘤細(xì)胞生物標(biāo)志物  
    抗體來(lái)源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
    產(chǎn)品應(yīng)用WB=1:500-2000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量40kDa
    細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human ZNF379/ZDHHC9:118-155/364 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010].

    Function:
    The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.

    Subunit:
    Interacts with GOLGA7.

    Subcellular Location:
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.

    DISEASE:
    Defects in ZDHHC9 are the cause of mental retardation syndromic X-linked ZDHHC9-related (MRXSZ) [MIM:300799]. A disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Some patients have marfanoid habitus as an additional feature.

    Similarity:
    Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
    Contains 1 DHHC-type zinc finger.

    SWISS:
    Q9Y397

    Gene ID:
    51114

    Database links:
    Entrez Gene: 51114 Human
    Entrez Gene: 208884 Mouse
    Entrez Gene: 302808 Rat
    Omim: 300646 Human
    SwissProt: Q9Y397 Human
    SwissProt: P59268 Mouse
    Unigene: 193566 Human
    Unigene: 207367 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















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