<strike id="amuic"></strike>
  • <abbr id="amuic"><option id="amuic"></option></abbr>
    <strike id="amuic"></strike>
    

  • <cite id="amuic"><source id="amuic"></source></cite>

    <cite id="amuic"><source id="amuic"></source></cite>
    • <ul id="amuic"><table id="amuic"></table></ul>
    


    
    
    
        
        
    
    
    

    

    
    
    
    
    
        
        
    
    
        
    

    

    
    
    
    
    
        
        
    
    
    
    最近搜索：細胞培養 微生物學 分子生物 生物化學 
    

    

    
	
    首頁>>免疫學>>一抗>>G蛋白α亞單位蛋白Q抗體  
    

    

    
	
    
    	
    
        	
    G蛋白α亞單位蛋白Q抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
    • 
                        	
      產品貨號：
      
                            
      BN41193R
      
                        
      • 
                    	
    • 
                        	
      中文名稱：
      
                            
      G蛋白α亞單位蛋白Q抗體 
      
                        
      • 
                                            	
    • 
                        	
      英文名稱：
      
                            
      Rabbit anti-GNAQ Polyclonal antibody 
      
                        
      • 
                                                                    	
    • 
                        	
      品牌：
      
                            
      Biorigin 
      
                        
      • 
                    
    
                
    
            
    
            
    
                    
    
                        
      
                            
    • 
                                
      貨號
      
                                
      產品規格
      
                                
      售價
      
                                
      備注
      
                            
      • 
                                                        
    • 
                                
      BN41193R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)   推薦應用：WB,ELISA
      
                            
      • 
                                                        
    • 
                                
      BN41193R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)   推薦應用：WB,ELISA
      
                            
      • 
                                                    
    
                    
    
              
    
            
    
            	
    
                	
    產品描述
    
                
    
                
    
                	
    英文名稱GNAQ
    中文名稱G蛋白α亞單位蛋白Q抗體
    別    名G ALPHA q; G protein alpha Q; GAQ; Guanine nucleotide binding protein alpha q; Guanine nucleotide binding protein G q subunit alpha; GNAQ_HUMAN.  
    研究領域腫瘤  心血管  細胞生物  神經生物學  信號轉導  G蛋白偶聯受體  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量42kDa
    細胞定位細胞核 細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human GNAQ:51-150/359 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹GNAQ belong to the family of heterotrimeric Guanine nucleotide-binding proteins proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. GNAQ is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta. in recent studies over expression of GNAQ is associated with cardiomyocyte apoptosis.

    Function:
    Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).

    Subunit:
    G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Binds SLC9A3R1. Forms a complex with PECAM1 and BDKRB2. Interacts with PECAM1.

    Subcellular Location:
    Nucleus (By similarity). Membrane (By similarity). Nucleus membrane (By similarity). Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity).

    Tissue Specificity:
    Predominantly expressed in ovary, prostate, testis and colon.

    Similarity:
    Belongs to the G-alpha family. G(q) subfamily.

    SWISS:
    P50148

    Gene ID:
    2776

    Database links:
    Entrez Gene: 2776 Human
    Entrez Gene: 14682 Mouse
    Entrez Gene: 654405 Pig
    Entrez Gene: 81666 Rat
    Omim: 600998 Human
    SwissProt: P50148 Human
    SwissProt: P21279 Mouse
    SwissProt: Q2PKF4 Pig
    SwissProt: P82471 Rat
    Unigene: 269782 Human
    Unigene: 439701 Mouse
    Unigene: 441601 Mouse
    Unigene: 22817 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    Gαq是G蛋白家族成員之一,是Gq蛋白的功能單位。其功能為傳導來自GPCR的信號到細胞內。研究證明,Gαq與免疫細胞活化、增殖、死亡、分化、遷移,細胞因子分泌以及自身免疫等均有非常密切的關系。