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    最近搜索:細胞培養 微生物學 分子生物 生物化學
    首頁>>免疫學>>一抗>>轉錄因子MYB相關蛋白B抗體
    轉錄因子MYB相關蛋白B抗體
    • 產品貨號:
      BN41182R
    • 中文名稱:
      轉錄因子MYB相關蛋白B抗體
    • 英文名稱:
      Rabbit anti-B MyB Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41182R-100ul

      100ul

      ¥2360.00

      交叉反應:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit) 推薦應用:IHC-P,IHC-F,IF,ELISA

    • BN41182R-200ul

      200ul

      ¥3490.00

      交叉反應:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit) 推薦應用:IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱B MyB
    中文名稱轉錄因子MYB相關蛋白B抗體
    別    名B-Myb; BMyB; MYB L2; Myb related protein B; Myb-like protein 2; Myb-related protein B; MybB; MYBB_HUMAN; MYBL 2; Mybl2; v myb avian myeloblastosis viral oncogene homolog like 2; v myb myeloblastosis viral oncogene homolog (avian) like 2; v myb myeloblastosis viral oncogene homolog like 2.  
    研究領域腫瘤  細胞生物  免疫學  染色質和核信號  信號轉導  轉錄調節因子  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, )
    產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:200-800 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量77kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human B MyB:101-200/700 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in the regulation of cell survival, proliferation, and differentiation. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes.

    Subunit:
    Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL22.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.

    Similarity:
    Contains 3 HTH myb-type DNA-binding domains.

    SWISS:
    P10244

    Gene ID:
    4605

    Database links:

    Entrez Gene: 4605 Human

    Entrez Gene: 17865 Mouse

    Entrez Gene: 296344 Rat

    Omim: 601415 Human

    SwissProt: P10244 Human

    SwissProt: P48972 Mouse

    Unigene: 179718 Human

    Unigene: 4594 Mouse

    Unigene: 20824 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.