<strike id="amuic"></strike>
  • <abbr id="amuic"><option id="amuic"></option></abbr>
    <strike id="amuic"></strike>
    

  • <cite id="amuic"><source id="amuic"></source></cite>

    <cite id="amuic"><source id="amuic"></source></cite>
    • <ul id="amuic"><table id="amuic"></table></ul>
    


    
    
    
        
        
    
    
    

    

    
    
    
    
    
        
        
    
    
        
    

    

    
    
    
    
    
        
        
    
    
    
    最近搜索：細胞培養 微生物學 分子生物 生物化學 
    

    

    
	
    首頁>>免疫學>>一抗>>5'肌苷磷酸脫氫酶2抗體  
    

    

    
	
    
    	
    
        	
    5'肌苷磷酸脫氫酶2抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
    • 
                        	
      產品貨號：
      
                            
      BN41177R
      
                        
      • 
                    	
    • 
                        	
      中文名稱：
      
                            
      5'肌苷磷酸脫氫酶2抗體 
      
                        
      • 
                                            	
    • 
                        	
      英文名稱：
      
                            
      Rabbit anti-IMPDH2 Polyclonal antibody 
      
                        
      • 
                                                                    	
    • 
                        	
      品牌：
      
                            
      Biorigin 
      
                        
      • 
                    
    
                
    
            
    
            
    
                    
    
                        
      
                            
    • 
                                
      貨號
      
                                
      產品規格
      
                                
      售價
      
                                
      備注
      
                            
      • 
                                                        
    • 
                                
      BN41177R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)   推薦應用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
      • 
                                                        
    • 
                                
      BN41177R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)   推薦應用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
      • 
                                                    
    
                    
    
              
    
            
    
            	
    
                	
    產品描述
    
                
    
                
    
                	
    英文名稱IMPDH2
    中文名稱5'肌苷磷酸脫氫酶2抗體
    別    名IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP oxireductase 2; IMPD 2; IMPD2; IMPDH 2; IMPDH II; IMPDH-II; Impdh2; IMPDHII; Inosine 5' monophosphate dehydrogenase 2; Inosine-5''-monophosphate dehydrogenase 2; IMDH2_HUMAN.  
    研究領域腫瘤  免疫學  信號轉導  生長因子和激素  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量56kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human IMPDH2:441-514/514 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.

    Function:
    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

    Subunit:
    Homotetramer.

    Subcellular Location:
    Cytoplasm. Nucleus.

    Tissue Specificity:
    IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.

    Post-translational modifications:
    The N-terminus is blocked.

    Similarity:
    Belongs to the IMPDH/GMPR family.
    Contains 2 CBS domains.

    SWISS:
    P12268

    Gene ID:
    3615

    Database links:
    Entrez Gene: 3615 Human
    Entrez Gene: 23918 Mouse
    Entrez Gene: 301005 Rat
    Omim: 146691 Human
    SwissProt: P12268 Human
    SwissProt: P24547 Mouse
    SwissProt: E9PU28 Rat
    Unigene: 654400 Human
    Unigene: 6065 Mouse
    Unigene: 8093 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













    image.png
    image.png