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    首頁>>免疫學>>一抗>>線粒體乙酰化酶3抗體  
    

    

    
	
    
    	
    
        	
    線粒體乙酰化酶3抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN41131R
      
                        
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      中文名稱：
      
                            
      線粒體乙酰化酶3抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-SIRT3 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      BN41131R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse(predicted:Rat)   推薦應用：WB,IHC-P,IHC-F,ICC
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱SIRT3
    中文名稱線粒體乙酰化酶3抗體
    別    名hSIRT3; hSIRT 3; hSIRT3; Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase; NAD dependent deacetylase sirtuin 3 mitochondrial; NAD-dependent deacetylase sirtuin-3, mitochondrial; Silent mating type information regulation 2 S.cerevisiae homolog 3; Sir 2 like 3; SIR 2 like protein 3; SIR 3; SIR2 L3; Sir2 like 3; SIR2 like protein 3; SIR2-like protein 3; SIR2L3; SIRT 3; SIRT3_HUMAN; Sirtuin 3; Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae); Sirtuin type 3; Sirtuin3.  
    研究領域腫瘤  心血管  細胞生物  細胞周期蛋白  線粒體  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Rat, )
    產品應用WB=1:500-1000 IHC-P=1:20-50 IHC-F=1:20-50 ICC=1:100 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量28/43kDa
    細胞定位細胞漿 線粒體
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human SIRT3:300-399/399 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMedPubMed
    產品介紹NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

    Function:
    NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

    Subunit:
    Interacts with NDUFA9, ACSS1, IDH2 and GDH.

    Subcellular Location:
    Mitochondrion matrix.

    Tissue Specificity:
    Widely expressed.

    Post-translational modifications:
    Processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product. Such processing is probably essential for its enzymatic activity.

    Similarity:
    Belongs to the sirtuin family. Contains 1 deacetylase sirtuin-type domain.

    SWISS:
    Q9NTG7

    Gene ID:
    23410

    Database links:
    Entrez Gene: 23410 Human
    Entrez Gene: 64384 Mouse
    Omim: 604481 Human
    SwissProt: Q9NTG7 Human
    SwissProt: Q8R104 Mouse
    Unigene: 716456 Human
    Unigene: 244216 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.