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    首頁>>免疫學>>一抗>>磷酸化乳腺癌易感基因相互作用蛋白1抗體  
    

    

    
	
    
    	
    
        	
    磷酸化乳腺癌易感基因相互作用蛋白1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號：
      
                            
      BN41058R
      
                        
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      中文名稱：
      
                            
      磷酸化乳腺癌易感基因相互作用蛋白1抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-phospho-BRIP1/BACH1 (Ser990) Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價
      
                                
      備注
      
                            
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      BN41058R-100ul
      
                                
      100ul
      
                                
      ￥2470.00
      
                                
      交叉反應：Human,Mouse(predicted:Cow,Sheep)   推薦應用：IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱phospho-BRIP1/BACH1 (Ser990)
    中文名稱磷酸化乳腺癌易感基因相互作用蛋白1抗體
    別    名BACH 1; BACH-1; BRAC 1 Associated C Terminal Helicase 1; BRCA 1 Interacting Protein 1; BRCA1 binding helicase like protein BACH1; BRCA1 interacting protein C terminal helicase 1; BRIP 1; BRIP-1; FANCJ; ATP dependent RNA helicase BRIP1; Fanconi anemia group J protein; FLJ90232; MGC126521; MGC126523; OF antibody Protein FACJ; FANCJ_HUMAN.  
    產(chǎn)品類型磷酸化抗體 
    研究領域腫瘤  免疫學  信號轉導  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse,  (predicted: Cow, Sheep, )
    產(chǎn)品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量141kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated Synthesised phosphopeptide derived from human BRIP1 around the phosphorylation site of Ser990:ST(p-S)PT 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009].

    Function:
    Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.

    Subcellular Location:
    Nucleus.

    Similarity:
    Belongs to the bZIP family. CNC subfamily.
    Contains 1 BTB (POZ) domain.
    Contains 1 bZIP domain.

    SWISS:
    Q9BX63

    Gene ID:
    83990

    Database links:
    Entrez Gene: 83990 Human
    Omim: 605882 Human
    SwissProt: Q9BX63 Human
    Unigene: 128903 Human


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications