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    最近搜索:細胞培養 微生物學 分子生物 生物化學
    首頁>>免疫學>>一抗>>磷酸吡哆醇氧化酶抗體
    磷酸吡哆醇氧化酶抗體
    • 產品貨號:
      BN41041R
    • 中文名稱:
      磷酸吡哆醇氧化酶抗體
    • 英文名稱:
      Rabbit anti-PNPO Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN41041R-100ul

      100ul

      ¥2360.00

      交叉反應:Rat(predicted:Human,Mouse) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    • BN41041R-200ul

      200ul

      ¥3490.00

      交叉反應:Rat(predicted:Human,Mouse) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

    產品描述

    英文名稱PNPO
    中文名稱磷酸吡哆醇氧化酶抗體
    別    名PDXPO; PNPO; PNPO_HUMAN; Pyridoxal 5' phosphate synthase; pyridoxamine 5' phosphate oxidase; Pyridoxamine phosphate oxidase; Pyridoxamine-phosphate oxidase; pyridoxine 5' phosphate oxidase; Pyridoxine-5''-phosphate oxidase; EC 1.4.3.5; FLJ10535.  
    研究領域腫瘤  細胞生物  免疫學  轉錄調節因子  激酶和磷酸酶  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Rat,  (predicted: Human, Mouse, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量29kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human PNPO:41-140/261 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

    Function:
    Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

    Subunit:
    Homodimer.

    DISEASE:
    Defects in PNPO are the cause of pyridoxine-5'-phosphate oxidase deficiency (PNPO deficiency) [MIM:610090]; also known as PNPO-related neonatal epileptic encephalopathy. The main feature of neonatal epileptic encephalopathy is the onset within hours of birth of a severe seizure disorder that does not respond to anticonvulsant drugs and can be fatal. Seizures can cease with the administration of PLP, being resistant to treatment with pyridoxine.

    Similarity:
    Belongs to the pyridoxamine 5'-phosphate oxidase family.

    SWISS:
    Q9NVS9

    Gene ID:
    55163

    Database links:

    Entrez Gene: 55163 Human

    Entrez Gene: 103711 Mouse

    Entrez Gene: 64533 Rat

    Omim: 603287 Human

    SwissProt: Q9NVS9 Human

    SwissProt: Q91XF0 Mouse

    SwissProt: O88794 Rat

    Unigene: 631742 Human

    Unigene: 254704 Mouse

    Unigene: 158883 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    PNPO是維生素B6(VB6)代謝的關鍵酶,參與催化氨基酸代謝的各種反應和其它多種代謝過程。