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    首頁>>免疫學>>一抗>>NADH脫氫酶黃素蛋白1抗體  
    

    

    
	
    
    	
    
        	
    NADH脫氫酶黃素蛋白1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40985R
      
                        
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      中文名稱：
      
                            
      NADH脫氫酶黃素蛋白1抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-NDUFV1 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      BN40985R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse)   推薦應用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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      BN40985R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse)   推薦應用：WB,IHC-P,IHC-F,IF,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱NDUFV1
    中文名稱NADH脫氫酶黃素蛋白1抗體
    別    名CI 51kD; Complex I 51kD; NADH dehydrogenase (ubiquinone) flavoprotein 1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; NADH dehydrogenase flavoprotein 1; NADH ubiquinone oxidoreductase 51 kDa subunit; NADH ubiquinone oxidoreductase; NDUFV 1; UQOR1; NDUV1_HUMAN.  
    研究領域腫瘤  細胞生物  免疫學  線粒體  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量49kDa
    細胞定位細胞漿 細胞膜 線粒體
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human NDUFV1:41-140/464 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]

    Function:
    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

    Subunit:
    Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

    Subcellular Location:
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

    DISEASE:
    Defects in NDUFV1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.

    Similarity:
    Belongs to the complex I 51 kDa subunit family.

    SWISS:
    P49821

    Gene ID:
    4723

    Database links:
    Entrez Gene: 287014 Cow
    Entrez Gene: 4723 Human
    Entrez Gene: 17995 Mouse
    Entrez Gene: 293655 Rat
    Omim: 161015 Human
    SwissProt: P25708 Cow
    SwissProt: P49821 Human
    SwissProt: Q91YT0 Mouse
    SwissProt: Q5XIH3 Rat
    Unigene: 7744 Human
    Unigene: 29842 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application
















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