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    首頁(yè)>>免疫學(xué)>>一抗>>細(xì)胞色素P450 2R1抗體  
    

    

    
	
    
    	
    
        	
    細(xì)胞色素P450 2R1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN40977R
      
                        
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      中文名稱(chēng)：
      
                            
      細(xì)胞色素P450 2R1抗體 
      
                        
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      英文名稱(chēng)：
      
                            
      Rabbit anti-CYP2R1 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
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      BN40977R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Pig,Horse,Rabbit)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
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      BN40977R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Human,Mouse(predicted:Rat,Dog,Pig,Horse,Rabbit)   推薦應(yīng)用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱(chēng)CYP2R1
    中文名稱(chēng)細(xì)胞色素P450 2R1抗體
    別    名Cytochrome P450 2R1; Cytochrome P450 family 2 R1; Cytochrome P450 family 2 subfamily R polypeptide 1; EC 1.14.13.15; MGC4663; Vitamin D 25 hydroxylase.  
    研究領(lǐng)域腫瘤  心血管  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
    抗體來(lái)源Rabbit
    克隆類(lèi)型Polyclonal
    交叉反應(yīng)Human, Mouse,  (predicted: Rat, Dog, Pig, Horse, Rabbit, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量55kDa
    細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CYP2R1:251-350/501 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.

    Subunit:
    Homodimer.

    Subcellular Location:
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

    Tissue Specificity:
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

    Similarity:
    Belongs to the cytochrome P450 family.

    SWISS:
    Q6VVX0

    Gene ID:
    120227

    Database links:
    Entrez Gene: 120227 Human
    Entrez Gene: 244209 Mouse
    Omim: 608713 Human
    SwissProt: Q6VVX0 Human
    SwissProt: Q6VVW9 Mouse
    Unigene: 371427 Human
    Unigene: 108037 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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