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最近搜索：細胞培養(yǎng) 微生物學分子生物生物化學

首頁>>免疫學>>一抗>>G蛋白結合蛋白RAB6A抗體

G蛋白結合蛋白RAB6A抗體

產品貨號：

BN40813R
中文名稱：

G蛋白結合蛋白RAB6A抗體
英文名稱：

Rabbit anti-RAB6A Polyclonal antibody
品牌：

Biorigin

貨號

產品規(guī)格

售價

備注
BN40813R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB
BN40813R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB

產品描述

英文名稱	RAB6A
中文名稱	G蛋白結合蛋白RAB6A抗體
別名	GTP binding protein RAB6B; Oncogene RAB6; Rab GTPase; Rab6A variant 3; Rab 6; RAB6; RAB6 member RAS oncogene family; RAB6A member RAS oncogene family; Ras related protein Rab 6A; RCO4 3; RAB6A_HUMAN.
研究領域	信號轉導 G蛋白偶聯(lián)受體 G蛋白信號
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用	WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	23kDa
細胞定位	細胞漿細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human RAB6A:121-208/208
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves, at each stage, the movement of carrier vesicles; a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the Sec4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. At least eight members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway. Rab 6, also known as RAB6B, RAB6A or RAB6A, is a 208 amino acid protein that is ubiquitously expressed and is a member of the small GTPase superfamily. Function: RAB6A belongs to the small GTPase superfamily. It may be involved in protein transport. It is a regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) and has a low GTPase activity. Subunit: Interacts with CCDC64; leads to its accumulation in the pericentrosomal region (By similarity). Interacts with SCYL1BP1. Interacts with VSP52 and RABGAP1. Interacts with GCC2 (via its GRIP domain). Interacts with RAB6IP1 (via its RUN 1 domain). Isoform 1 interacts with RAB6KIFL. Isoform 2 does not interact with RAB6KIFL. Isoform 1 interacts with BICD1. Isoform 2 interacts with BICD1. Isoform 1 interacts with BICD2. Isoform 2 interacts with BICD2. Interacts with TMF1. Isoform 1 (GTP-bound) interacts with DYNLRB1; the interaction is direct. Isoform 2 (GDP-bound) interacts with DYNLRB1; the interaction is direct. Interacts with PIFO. Subcellular Location: Golgi apparatus membrane; Lipid-anchor. Tissue Specificity: Ubiquitous. Similarity: Belongs to the small GTPase superfamily. Rab family. SWISS: P20340 Gene ID: 5870 Database links: Entrez Gene: 5870 Human Entrez Gene: 19346 Mouse Entrez Gene: 84379 Rat Omim: 179513 Human SwissProt: P20340 Human SwissProt: P35279 Mouse SwissProt: Q9WVB1 Rat Unigene: 503222 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.