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    首頁>>免疫學>>一抗>>環指蛋白43抗體  
    

    

    
	
    
    	
    
        	
    環指蛋白43抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40812R
      
                        
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      中文名稱：
      
                            
      環指蛋白43抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-RNF43 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      備注
      
                            
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      BN40812R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse)   推薦應用：WB,IHC-P
      
                            
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      BN40812R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse)   推薦應用：WB,IHC-P
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱RNF43
    中文名稱環指蛋白43抗體
    別    名RNF124; Ring finger protein 43; URCC; RNF43_HUMAN; E3 ubiquitin-protein ligase RNF43; RING finger protein 43.  
    研究領域腫瘤  細胞生物  腫瘤細胞生物標志物  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, )
    產品應用WB=1:500-2000 IHC-P=1:400-800 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量83kDa
    細胞定位細胞核 細胞漿 細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human RNF43:401-500/783 <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹RNF43 is a probable E3 ubiquitin-protein ligase that promotes cell growth and is upregulated in colon cancer. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

    Function:
    Probable E3 ubiquitin-protein ligase. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

    Subunit:
    Interacts with AKAP8L, NONO and SFPQ.

    Subcellular Location:
    Endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential). Nucleus envelope.

    Tissue Specificity:
    Expressed in fetal kidney, fetal lung, in colon cancer tissues, hepatocellular carcinomas and lung adenocarcinomas. Overexpressed in colorectal cancer cell lines.

    Similarity:
    Contains 1 RING-type zinc finger.

    SWISS:
    Q68DV7

    Gene ID:
    54894

    Database links:
    Entrez Gene: 54894 Human
    Entrez Gene: 207742 Mouse
    Entrez Gene: 303412 Rat
    Omim: 612482 Human
    SwissProt: Q68DV7 Human
    SwissProt: Q5NCP0 Mouse
    Unigene: 584916 Human
    Unigene: 440230 Mouse
    Unigene: 214174 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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