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    首頁>>免疫學>>一抗>>谷胱甘肽S轉移酶A3抗體  
    

    

    
	
    
    	
    
        	
    谷胱甘肽S轉移酶A3抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40741R
      
                        
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      中文名稱：
      
                            
      谷胱甘肽S轉移酶A3抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-GSTA3 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      備注
      
                            
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      BN40741R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Rat(predicted:Mouse)   推薦應用：WB
      
                            
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      BN40741R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Rat(predicted:Mouse)   推薦應用：WB
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱GSTA3
    中文名稱谷胱甘肽S轉移酶A3抗體
    別    名Glutathione S alkyltransferase A3; Glutathione S aralkyltransferase A3; Glutathione S aryltransferase A3; Glutathione S transferase A3 3; Glutathione S transferase A3; Glutathione S transferase alpha 3; Glutathione transferase alpha 3; GST class alpha; GST class alpha member 3; GSTA 3; GSTA3 3; GTA 3; GTA3; GTA-3; MGC22232; S (hydroxyalkyl)glutathione lyase A3; GSTA3_HUMAN.  
    研究領域細胞生物  免疫學  信號轉導  轉錄調節因子  激酶和磷酸酶  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Rat,  (predicted: Mouse, )
    產品應用WB=1:500-2000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量25kDa
    細胞定位細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from mouse GSTA3:51-150/221 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Glutathione S-transferase A3 (GSTA3) belongs to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. GSTA3 catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones.

    Function:
    Conjugation of reduced glutathione to a wide number ofexogenous and endogenous hydrophobic electrophiles. Catalyzesisomerization reactions that contribute to the biosynthesis ofsteroid hormones. Efficiently catalyze obligatory double-bondisomerizations of delta(5)-androstene-3,17-dione anddelta(5)-pregnene-3,20-dione, precursors to testosterone andprogesterone, respectively.

    Subunit:
    Homodimer.

    Subcellular Location:
    Cytoplasm.

    Similarity:
    Belongs to the GST superfamily. Alpha family.
    Contains 1 GST C-terminal domain.
    Contains 1 GST N-terminal domain.

    SWISS:
    P30115

    Gene ID:
    14859

    Database links:
    Entrez Gene: 2940 Human
    Entrez Gene: 14859 Mouse
    Entrez Gene: 24421 Rat
    Omim: 605449 Human
    SwissProt: Q16772 Human
    SwissProt: P30115 Mouse
    SwissProt: P04904 Rat
    Unigene: 102484 Human
    Unigene: 394593 Mouse
    Unigene: 10460 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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