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    首頁>>免疫學>>一抗>>原癌基因M-ras抗體  
    

    

    
	
    
    	
    
        	
    原癌基因M-ras抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40731R
      
                        
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      中文名稱：
      
                            
      原癌基因M-ras抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-MRas Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      備注
      
                            
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      BN40731R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Mouse,Rat   推薦應用：WB
      
                            
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      BN40731R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Mouse,Rat   推薦應用：WB
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱MRas
    中文名稱原癌基因M-ras抗體
    別    名M-RAS; M ras; muscle RAS oncogene homolog precursor; Muscle and microspikes Ras; Muscle Ras oncogene homologue; R ras3; R-ras3; Ras related protein MRas; Ras related protein RRas3; RRas3; XRas.  
    研究領域腫瘤  細胞生物  免疫學  細胞凋亡  轉錄調節因子  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat, 
    產品應用WB=1:500-2000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量23kDa
    細胞定位細胞漿 細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from mouse MRas:201-259/259 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling.

    Function:
    May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.

    Subcellular Location:
    Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).

    Tissue Specificity:
    Expression highly restricted to the brain and heart.

    Similarity:
    Belongs to the small GTPase superfamily. Ras family.

    SWISS:
    O08989

    Gene ID:
    17532

    Database links:
    Entrez Gene: 22808 Human
    Entrez Gene: 17532 Mouse
    Entrez Gene: 25482 Rat
    Omim: 608435 Human
    SwissProt: O14807 Human
    SwissProt: O08989 Mouse
    SwissProt: P97538 Rat
    Unigene: 527021 Human
    Unigene: 2045 Mouse
    Unigene: 10641 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    M-ras癌變基因的表達產物Ras蛋白存在于多數腫瘤之中，目前是腫瘤研究較重要的蛋白之一.












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