<strike id="amuic"></strike>
  • <abbr id="amuic"><option id="amuic"></option></abbr>
    <strike id="amuic"></strike>
    

  • <cite id="amuic"><source id="amuic"></source></cite>

    <cite id="amuic"><source id="amuic"></source></cite>
    • <ul id="amuic"><table id="amuic"></table></ul>
    


    
    
    
        
        
    
    
    

    

    
    
    
    
    
        
        
    
    
        
    

    

    
    
    
    
    
        
        
    
    
    
    最近搜索：細胞培養 微生物學 分子生物 生物化學 
    

    

    
	
    首頁>>免疫學>>一抗>>鋅轉運體8蛋白抗體  
    

    

    
	
    
    	
    
        	
    鋅轉運體8蛋白抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
    • 
                        	
      產品貨號：
      
                            
      BN40708R
      
                        
      • 
                    	
    • 
                        	
      中文名稱：
      
                            
      鋅轉運體8蛋白抗體 
      
                        
      • 
                                            	
    • 
                        	
      英文名稱：
      
                            
      Rabbit anti-ZNT8 Polyclonal antibody 
      
                        
      • 
                                                                    	
    • 
                        	
      品牌：
      
                            
      Biorigin 
      
                        
      • 
                    
    
                
    
            
    
            
    
                    
    
                        
      
                            
    • 
                                
      貨號
      
                                
      產品規格
      
                                
      售價
      
                                
      備注
      
                            
      • 
                                                        
    • 
                                
      BN40708R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Rat(predicted:Human,Mouse)   推薦應用：IHC-P
      
                            
      • 
                                                        
    • 
                                
      BN40708R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Rat(predicted:Human,Mouse)   推薦應用：IHC-P
      
                            
      • 
                                                    
    
                    
    
              
    
            
    
            	
    
                	
    產品描述
    
                
    
                
    
                	
    英文名稱ZNT8
    中文名稱鋅轉運體8蛋白抗體
    別    名SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; Zinc transporter 8; zinc transporter ZnT-8; ZnT-8; ZNT 8; ZNT8_HUMAN.  
    研究領域細胞生物  免疫學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Rat,  (predicted: Human, Mouse, )
    產品應用IHC-P=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量41kDa
    細胞定位細胞漿 細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human ZNT8:1-100/369 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].

    Function:
    Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells

    Subunit:
    Homodimer (By similarity).

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein (Probable). Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein (Probable). Note=Associated with insulin and glucagon secretory granules (By similarity).

    Tissue Specificity:
    In the endocrine pancreas, expressed in insulin-producing beta cells. Expressed at relatively high levels in subcutaneous fat tissue from lean persons; much lower levels in visceral fat, whether from lean or obese individuals, and in subcutaneous fat tissue from obese individuals. Expressed in peripheral blood mononuclear cells, including T-cells and B-cells, with great variation among individuals ranging from negative to strongly positive.

    Similarity:
    Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.

    SWISS:
    Q8IWU4

    Gene ID:
    169026

    Database links:
    Entrez Gene: 169026 Human
    Omim: 611145 Human
    SwissProt: Q8IWU4 Human
    Unigene: 532270 Human


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















    image.png