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    首頁>>免疫學>>一抗>>結締組織生長因子抗體  
    

    

    
	
    
    	
    
        	
    結締組織生長因子抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40687R
      
                        
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      中文名稱：
      
                            
      結締組織生長因子抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-CTGF Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      BN40687R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Rabbit)   推薦應用：WB
      
                            
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      BN40687R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Rabbit)   推薦應用：WB
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱CTGF
    中文名稱結締組織生長因子抗體
    別    名CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; CTGF; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN.  
    研究領域心血管  免疫學  生長因子和激素  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Rabbit, )
    產品應用WB=1:500-2000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量36kDa
    細胞定位細胞外基質 分泌型蛋白 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CTGF:27-120/349 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009].

    Function:
    Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

    Subunit:
    Monomer.

    Subcellular Location:
    Secreted, extracellular space, extracellular matrix. Secreted.

    Tissue Specificity:
    Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.

    Similarity:
    Belongs to the CCN family.
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
    Contains 1 IGFBP N-terminal domain.
    Contains 1 TSP type-1 domain.
    Contains 1 VWFC domain.

    SWISS:
    P29279

    Gene ID:
    1490

    Database links:
    Entrez Gene: 1490 Human
    Entrez Gene: 64032 Rat
    Omim: 121009 Human
    SwissProt: P29279 Human
    SwissProt: P29268 Mouse
    SwissProt: Q9R1E9 Rat
    Unigene: 410037 Human
    Unigene: 390287 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    生長因子和激素（ Growth Factor and Hormones）
    結締組織生長因子（CTGF）是調節細胞增生、分化和細胞外基質形成的重要效應分子,可調節機體有關組織、細胞生長并與纖維化發生密切相關的一種因子，因而在肌體的各類創傷修復過程中具有重要的生理學意義。


















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