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    首頁>>免疫學>>一抗>>鱗狀細胞癌增強蛋白1抗體  
    

    

    
	
    
    	
    
        	
    鱗狀細胞癌增強蛋白1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40684R
      
                        
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      中文名稱：
      
                            
      鱗狀細胞癌增強蛋白1抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-GASC1/KDM4C Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      備注
      
                            
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      BN40684R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)   推薦應用：WB,ELISA
      
                            
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      BN40684R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)   推薦應用：WB,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱GASC1/KDM4C
    中文名稱鱗狀細胞癌增強蛋白1抗體
    別    名GASC 1 protein; GASC1 antibody Gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain containing histone demethylation protein 3C; Jumonji domain containing protein 2C; KDM4C_HUMAN.  
    研究領域腫瘤  免疫學  染色質和核信號  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
    產品應用WB=1:500-2000 ELISA=1:500-5000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量120kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human GASC1/KDM4C:291-390/1056 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹KDM4C/JMJD2C, a jumonji domain containing protein, is a histone demethylase. JMJD2C specifically demethylates Lysine 9 and Lysine 36 residues of Histone H3, thereby playing a central role in regulating histone modifications.

    Function:
    Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Overexpressed in several esophageal squamous cell carcinomas (ESCs).

    Similarity:
    Belongs to the JHDM3 histone demethylase family.
    Contains 1 JmjC domain.
    Contains 1 JmjN domain.
    Contains 2 PHD-type zinc fingers.
    Contains 2 Tudor domains.

    SWISS:
    Q9H3R0

    Gene ID:
    23081

    Database links:
    Entrez Gene: 23081 Human
    Entrez Gene: 76804 Mouse
    Entrez Gene: 298144 Rat
    Omim: 605469 Human
    SwissProt: Q9H3R0 Human
    SwissProt: Q8VCD7 Mouse
    Unigene: 709425 Human
    Unigene: 209059 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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