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    最近搜索：細胞培養 微生物學 分子生物 生物化學 
    

    

    
	
    首頁>>免疫學>>一抗>>腦轉錄因子4蛋白抗體  
    

    

    
	
    
    	
    
        	
    腦轉錄因子4蛋白抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40646R
      
                        
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      中文名稱：
      
                            
      腦轉錄因子4蛋白抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-BRN4 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      BN40646R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)   推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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      BN40646R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：nan(predicted:Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)   推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱BRN4
    中文名稱腦轉錄因子4蛋白抗體
    別    名class 3; transcription factor 4; Brain specific homeobox POU domain protein 4; Brain-4; Brain-specific homeobox/POU domain protein 4; BRAIN4; Brn-4; BRN4; DFN3; Oct-9; Octamer-binding protein 9; Octamer-binding transcription factor 9; OTF-9; OTF9; PO3F4_HUMAN; POU domain; POU domain class 3 transcription factor 4; POU3F4.  
    研究領域腫瘤  細胞生物  免疫學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量51kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human BRN4:1-100/361 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) . A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness.

    Function:
    Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.

    Subunit:
    Homodimer. Heterodimer with a RAR molecule. Binds DNA preferentially as a RAR/RXR heterodimer.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Brain specific.

    DISEASE:
    Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) [MIM:304400]. A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness.

    Similarity:
    Belongs to the POU transcription factor family. Class-3 subfamily.
    Contains 1 homeobox DNA-binding domain.
    Contains 1 POU-specific domain.

    SWISS:
    P49335

    Gene ID:
    5456

    Database links:
    Entrez Gene: 5456 Human
    Entrez Gene: 18994 Mouse
    Entrez Gene: 29589 Rat
    Omim: 300039 Human
    SwissProt: P49335 Human
    SwissProt: P62515 Mouse
    SwissProt: P62516 Rat
    Unigene: 2229 Human
    Unigene: 405149 Mouse
    Unigene: 56946 Mouse
    Unigene: 33030 Rat
     


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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