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    首頁>>免疫學>>一抗>>鋅指RNA結合蛋白抗體  
    

    

    
	
    
    	
    
        	
    鋅指RNA結合蛋白抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40545R
      
                        
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      中文名稱：
      
                            
      鋅指RNA結合蛋白抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-ZFR Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      備注
      
                            
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      BN40545R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)   推薦應用：WB
      
                            
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      BN40545R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)   推薦應用：WB
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱ZFR
    中文名稱鋅指RNA結合蛋白抗體
    別    名FLJ41312; hZFR; M phase phosphoprotein homolog; M-phase phosphoprotein homolog; zfr; ZFR_HUMAN; zinc finger RNA binding protein; Zinc finger RNA-binding protein.  
    研究領域腫瘤  細胞凋亡  轉錄調節因子  結合蛋白  鋅指蛋白  表觀遺傳學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產品應用WB=1:500-2000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量117kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human ZFR:271-370/1074 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹ZFR is 1,074 amino acid RNA-binding protein. In human, ZFR is expressed in lung, liver, lymphocytes, heart, pancreas, kidney and placenta, and regulates postimplantation and gastrulation stages of development. Murine ZFR is observed in testis, ovary and brain. With elevated levels of expression during meiosis, ZFR associates with chromosome foci in meiotic cells. ZFR contains 1 DZF domain and localizes in the somatodendritic compartment of hippocampal neurons and colocalizes with STAU2 in cytosolic RNA granules. Knockout of ZFR in mouse embryo prevents the development of some embryonic structures leads to an increase in programmed cell death with a decrease in mitotic index.

    Function:
    Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA.

    Subcellular Location:
    Nucleus. Cytoplasm. Cytoplasmic granule. Chromosome. Associated with chromosome foci in meiotic cells. Localizes in somatodendritic compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules.

    Tissue Specificity:
    Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney.

    Similarity:
    Contains 1 DZF domain.

    SWISS:
    Q96KR1

    Gene ID:
    51663

    Database links:
    Entrez Gene: 51663 Human
    Entrez Gene: 22763 Mouse
    Entrez Gene: 365703 Rat
    Entrez Gene: 321659 Zebrafish
    SwissProt: Q96KR1 Human
    SwissProt: O88532 Mouse
    SwissProt: Q562A2 Rat
    SwissProt: Q6PCR6 Zebrafish
    Unigene: 435231 Human
    Unigene: 273496 Mouse
    Unigene: 11634 Rat
    Unigene: 26724 Zebrafish


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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