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    首頁(yè)>>免疫學(xué)>>一抗>>肝細(xì)胞核因子6抗體  
    

    

    
	
    
    	
    
        	
    肝細(xì)胞核因子6抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN40508R
      
                        
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      中文名稱：
      
                            
      肝細(xì)胞核因子6抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-HNF6 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
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      BN40508R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Sheep)   推薦應(yīng)用：WB,ELISA
      
                            
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      BN40508R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Cow,Horse,Sheep)   推薦應(yīng)用：WB,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱HNF6
    中文名稱肝細(xì)胞核因子6抗體
    別    名hepatocyte nuclear factor 6 alpha; Hepatocyte nuclear factor 6; HNF 6; HNF-6; HNF6_HUMAN; HNF6A; One cut domain family member 1; One cut homeobox 1; Onecut1.  
    研究領(lǐng)域腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  新陳代謝  表觀遺傳學(xué)  
    抗體來(lái)源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human, Mouse, Rat,  (predicted: Dog, Cow, Horse, Sheep, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量51kDa
    細(xì)胞定位細(xì)胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human HNF6:351-465/465 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

    Function:
    Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Highly expressed in liver; lower expression in testis and skin.

    Similarity:
    Belongs to the CUT homeobox family.
    Contains 1 CUT DNA-binding domain.
    Contains 1 homeobox DNA-binding domain.

    SWISS:
    Q9UBC0

    Gene ID:
    3175

    Database links:
    Entrez Gene: 3175 Human
    Entrez Gene: 15379 Mouse
    Entrez Gene: 25231 Rat
    Omim: 604164 Human
    SwissProt: Q9UBC0 Human
    SwissProt: O08755 Mouse
    SwissProt: P70512 Rat
    Unigene: 658573 Human
    Unigene: 303355 Mouse
    Unigene: 48812 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications