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    首頁>>免疫學>>一抗>>驅動蛋白家族成員13A抗體  
    

    

    
	
    
    	
    
        	
    驅動蛋白家族成員13A抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40481R
      
                        
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      中文名稱：
      
                            
      驅動蛋白家族成員13A抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-KIF13A Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      備注
      
                            
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      BN40481R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)   推薦應用：IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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      BN40481R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)   推薦應用：IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱KIF13A
    中文名稱驅動蛋白家族成員13A抗體
    別    名bA500C11.2; FLJ27232; KI13A_HUMAN; KIF 13A; Kif13a; Kinesin family member 13A; Kinesin like protein KIF13A; Kinesin like protein RBKIN; Kinesin-like protein KIF13A; Kinesin-like protein RBKIN; RBKIN.  
    研究領域細胞生物  免疫學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量202kDa
    細胞定位細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human KIF13A:1501-1600/1805 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

    Function:
    Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.

    Subcellular Location:
    Cytoplasm > cytoskeleton > centrosome. Midbody. Endosome membrane. Golgi apparatus membrane. Recruited to the midbody during cytokinesis.

    Tissue Specificity:
    Widely expressed, with highest levels in heart, brain and skeletal muscle.

    Similarity:
    Belongs to the kinesin-like protein family.
    Contains 1 FHA domain.
    Contains 1 kinesin-motor domain.

    SWISS:
    Q9H1H9

    Gene ID:
    63971

    Database links:
    Entrez Gene: 63971 Human
    Omim: 605433 Human
    SwissProt: Q9H1H9 Human
    Unigene: 94499 Human


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.