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    首頁>>免疫學>>一抗>>蛋白酶調解因子9抗體  
    

    

    
	
    
    	
    
        	
    蛋白酶調解因子9抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40436R
      
                        
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      中文名稱：
      
                            
      蛋白酶調解因子9抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-PSMD9 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      BN40436R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,GuineaPig)   推薦應用：IHC-P,IHC-F,IF,ELISA
      
                            
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      BN40436R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,GuineaPig)   推薦應用：IHC-P,IHC-F,IF,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱PSMD9
    中文名稱蛋白酶調解因子9抗體
    別    名Bridge-1; MGC8644; 26S proteasome non ATPase regulatory subunit 9; 26S proteasome regulatory subunit p27; Homolog of rat Bridge 1; p27; Proteasome (prosome macropain) 26S subunit non ATPase 9; Proteasome 26S non ATPase regulatory subunit 9; Proteasome 26S subunit non ATPase 9; PSMD 9; Rpn4; PSMD9_HUMAN.   
    研究領域免疫學  轉錄調節因子  糖尿病  內分泌病  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
    產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量25kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human PSMD9:65-150/223 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2012]

    Function:
    Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process.

    Subunit:
    Interacts with PSMC3. Part of a transient complex (modulator) containing PSMD9, PSMC6 and PSMC3 formed during the assembly of the 26S proteasome.

    Tissue Specificity:
    Expressed in all tissues tested, highly expressed in liver and kidney.

    Similarity:
    Belongs to the proteasome subunit p27 family.
    Contains 1 PDZ (DHR) domain.

    SWISS:
    O00233

    Gene ID:
    5715

    Database links:
    Entrez Gene: 5715 Human
    Entrez Gene: 67151 Mouse
    Omim: 603146 Human
    SwissProt: O00233 Human
    SwissProt: Q9CR00 Mouse
    Unigene: 131151 Human
    Unigene: 278997 Mouse


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    PSMD-9蛋白有可能增強激活胰島素的產生，主要用于二型糖尿病的研究。