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    首頁>>免疫學>>一抗>>CD53抗體  
    

    

    
	
    
    	
    
        	
    CD53抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40432R
      
                        
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      中文名稱：
      
                            
      CD53抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-CD53 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      BN40432R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human   推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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      BN40432R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human   推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱CD53
    中文名稱CD53抗體
    別    名AI323659; Antigen MOX44 identified by monoclonal; MRC-OX44; CD 53; CD53; CD53 antigen; CD53 antigen, isoform CRA_b; CD53 glycoprotein; Cd53 molecule; CD53 tetraspan antigen; CD53_HUMAN; Cell surface glycoprotein CD53; Leukocyte antigen MRC OX-44; Leukocyte surface antigen CD53; MOX 44; MOX44; OTTHUMP00000059505; Ox-44; OX44; RATOX44; Tetraspanin 25; Tetraspanin-25; Tetraspanin25; Transmembrane glycoprotein; TSPAN 25; Tspan-25; TSPAN25.  
    研究領域腫瘤  細胞生物  信號轉導  細胞粘附分子  細胞表面分子  糖蛋白  淋巴細胞  t-淋巴細胞  b-淋巴細胞  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Human, 
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量24kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human CD53:65-160/219 <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The CD53 antigen is a member of the tetraspanin membrane protein family that is expressed in the lymphoid-myeloid lineage. The tetraspanin superfamily (CD9, CD37, CD53, CD63, CD81 and CD82) comprises a group of cell-surface proteins that are involved in cell activation and signal transduction as well as in cell adhesion, motility and metastasis. Tetraspanin transmembrane proteins have a metastasis suppressor effect by acting as cell motility brakes in tumor cells. Human neutrophils express high levels of CD53, an N-glycosylated pan-leukocyte antigen and the true homolog of the rat MRC-OX-44 antigen. CD53 is expressed on B cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T cells.

    Function:
    Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).

    Subunit:
    Interacts with SCIMP.

    Subcellular Location:
    Membrane.

    Tissue Specificity:
    B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells.

    Similarity:
    Belongs to the tetraspanin (TM4SF) family.

    SWISS:
    P19397

    Gene ID:
    963

    Database links:
    Entrez Gene: 963 Human
    Omim: 151525 Human
    SwissProt: P19397 Human
    Unigene: 443057 Human


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.