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    最近搜索:細胞培養 微生物學 分子生物 生物化學
    首頁>>免疫學>>一抗>>果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗體
    果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗體
    • 產品貨號:
      BN40382R
    • 中文名稱:
      果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗體
    • 英文名稱:
      Rabbit anti-PFKFB3/PFK2 Polyclonal antibody
    • 品牌:
      Biorigin
    • 貨號

      產品規格

      售價

      備注

    • BN40382R-100ul

      100ul

      ¥2360.00

      交叉反應:Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用:IHC-P,IHC-F,ICC,IF,ELISA

    • BN40382R-200ul

      200ul

      ¥3490.00

      交叉反應:Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用:IHC-P,IHC-F,ICC,IF,ELISA

    產品描述

    英文名稱PFKFB3/PFK2
    中文名稱果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗體
    別    名6 phosphofructo 2 kinase/ fructose 2,6 bisphosphatase; 6 phosphofructo 2 kinase/fructose 2,6 biphosphatase 3; 6-bisphosphatase; 6-P2ase 3; 6-P2ASE brain/placenta-type isozyme; 6PF 2 K/Fru 2,6 P2ASE brain/placenta type isozyme; 6PF 2-K/Fru 2,6 P2ase 3; 6PF-2-K/Fru-2; F263_HUMAN; fructose 6 phosphate,2 kinase/fructose 2, 6 bisphosphatase; Fructose-2; Inducible 6 phosphofructo 2 kinase/fructose 2,6 bisphosphatase; iPFK 2; iPFK-2; IPFK2; PFK/FBPase 3; PFK2; PFKFB3; Renal carcinoma antigen NY REN 56; Renal carcinoma antigen NY-REN-56; uPFK 2.  
    研究領域細胞生物  神經生物學  信號轉導  激酶和磷酸酶  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量59kDa
    細胞定位細胞核 細胞漿 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human PFKFB3:421-520/520 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]

    Function:
    Synthesis and degradation of fructose 2,6-bisphosphate.

    Tissue Specificity:
    Ubiquitous.

    Post-translational modifications:
    Phosphorylation by AMPK stimulates activity.

    Similarity:
    In the C-terminal section; belongs to the phosphoglycerate mutase family.

    SWISS:
    Q16875

    Gene ID:
    5209

    Database links:

    Entrez Gene: 5209 Human

    Entrez Gene: 170768 Mouse

    Entrez Gene: 24640 Rat

    Omim: 605319 Human

    SwissProt: Q16875 Human

    SwissProt: P25114 Rat

    Unigene: 444304 Human

    Unigene: 44844 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications












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