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    首頁>>免疫學>>一抗>>神經降壓素受體2抗體  
    

    

    
	
    
    	
    
        	
    神經降壓素受體2抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40344R
      
                        
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      中文名稱：
      
                            
      神經降壓素受體2抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-Neurotensin Receptor 2 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
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      BN40344R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Human,Mouse(predicted:Rat,Dog,Cow,Rabbit,Sheep)   推薦應用：WB,ELISA
      
                            
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      BN40344R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Human,Mouse(predicted:Rat,Dog,Cow,Rabbit,Sheep)   推薦應用：WB,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱Neurotensin Receptor 2
    中文名稱神經降壓素受體2抗體
    別    名Levocabastine sensitive neurotensin receptor; Levocabastine-sensitive neurotensin receptor; Neurotensin receptor type 2; NT R 2; NT-R-2; NTR2; NTR2 receptor; NTR2_HUMAN; Ntsr2.  
    研究領域細胞生物  神經生物學  信號轉導  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse,  (predicted: Human, Rat, Dog, Cow, Rabbit, Sheep, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量45kDa
    細胞定位細胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Neurotensin Receptor 2:151-250/410 <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner.

    Function:
    Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.
    Neurotensin receptor subfamily. NTSR2 sub-subfamily.

    SWISS:
    O95665

    Gene ID:
    23620

    Database links:
    Entrez Gene: 23620 Human
    Entrez Gene: 18217 Mouse
    Entrez Gene: 64636 Rat
    Omim: 605538 Human
    SwissProt: O95665 Human
    SwissProt: P70310 Mouse
    SwissProt: Q63384 Rat
    Unigene: 131138 Human
    Unigene: 281715 Mouse
    Unigene: 127792 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.













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