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    首頁>>免疫學>>一抗>>生長激素釋放激素同源盒蛋白1抗體  
    

    

    
	
    
    	
    
        	
    生長激素釋放激素同源盒蛋白1抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產品貨號：
      
                            
      BN40318R
      
                        
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      中文名稱：
      
                            
      生長激素釋放激素同源盒蛋白1抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-Gsh1 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號
      
                                
      產品規格
      
                                
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      備注
      
                            
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      BN40318R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應：Mouse(predicted:Human,Rat,Dog,Pig,Sheep)   推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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      BN40318R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應：Mouse(predicted:Human,Rat,Dog,Pig,Sheep)   推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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    產品描述
    
                
    
                
    
                	
    英文名稱Gsh1
    中文名稱生長激素釋放激素同源盒蛋白1抗體
    別    名GS homeo box protein 1; GS homeobox 1; GSH1; GSX1; GSX1_HUMAN; Homeobox protein GSH-1 ; Homeobox protein Gsh1.  
    研究領域細胞生物  神經生物學  信號轉導  干細胞  表觀遺傳學  
    抗體來源Rabbit
    克隆類型Polyclonal
    交叉反應Mouse,  (predicted: Human, Rat, Dog, Pig, Sheep, )
    產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量28kDa
    細胞定位細胞核 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Gsh1:165-264/264 
    亞    型IgG
    純化方法affinity purified by Protein A
    儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產品介紹Growth hormone-releasing hormone (GHRH) stimulates secretion and synthesis of growth hormone (GH), causes somatotroph proliferation and may have direct actions in fetal/placental development, reproduction and immune function. It exerts its action through high-affinity GHRH receptors present in the anterior pituitary. GSH-1 (GS homeobox 1) is a 264 amino acid hypothalamic nuclear protein that functions as a transcription factor responsible for maintaining GHRH expression as well as playing an important role in pituitary development. Coexpression of CBP leads to significantly enhanced GSH-1-induced GHRH expression, which suggest that CBP may function as a co-activator. Knockdown of GSH-1 mRNA in mice causes a dwarf phenotype, which suggests that certain cases of familial dwarfism may be caused by a mutation of the GSH-1 gene.

    Function:
    Probable transcription factor that binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'. Activates the transcription of the GHRH gene. Plays an important role in pituitary development.

    Subcellular Location:
    Nucleus.

    Similarity:
    Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain.

    SWISS:
    Q9H4S2

    Gene ID:
    219409

    Database links:
    Entrez Gene: 219409 Human
    Entrez Gene: 14842 Mouse
    Entrez Gene: 288457 Rat
    SwissProt: Q9H4S2 Human
    SwissProt: P31315 Mouse
    Unigene: 351785 Human
    Unigene: 4797 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications












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