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    首頁(yè)>>免疫學(xué)>>一抗>>卵黃狀黃斑病蛋白4抗體  
    

    

    
	
    
    	
    
        	
    卵黃狀黃斑病蛋白4抗體
     
    
            
    
            	
    
            	
    
                	
      
                    	
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      產(chǎn)品貨號(hào)：
      
                            
      BN40279R
      
                        
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      中文名稱：
      
                            
      卵黃狀黃斑病蛋白4抗體 
      
                        
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      英文名稱：
      
                            
      Rabbit anti-Bestrophin 4 Polyclonal antibody 
      
                        
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      品牌：
      
                            
      Biorigin 
      
                        
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      貨號(hào)
      
                                
      產(chǎn)品規(guī)格
      
                                
      售價(jià)
      
                                
      備注
      
                            
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      BN40279R-100ul
      
                                
      100ul
      
                                
      ￥2360.00
      
                                
      交叉反應(yīng)：Human(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep)   推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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      BN40279R-200ul
      
                                
      200ul
      
                                
      ￥3490.00
      
                                
      交叉反應(yīng)：Human(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep)   推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA
      
                            
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    產(chǎn)品描述
    
                
    
                
    
                	
    英文名稱Bestrophin 4
    中文名稱卵黃狀黃斑病蛋白4抗體
    別    名BEST 4; BEST4; BEST-4; Bestrophin 4; Bestrophin4; Bestrophin-4; Vitelliform macular dystrophy 2 like 2; Vitelliform macular dystrophy 2 like protein 2; VMD2L2; BEST4_HUMAN.  
    研究領(lǐng)域腫瘤  信號(hào)轉(zhuǎn)導(dǎo)  通道蛋白  
    抗體來(lái)源Rabbit
    克隆類型Polyclonal
    交叉反應(yīng)Human,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量53kDa
    細(xì)胞定位細(xì)胞膜 
    性    狀Liquid
    濃    度1mg/ml
    免 疫 原KLH conjugated synthetic peptide derived from human Bestrophin 4:151-250/473 <Extracellular>
    亞    型IgG
    純化方法affinity purified by Protein A
    儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    PubMedPubMed
    產(chǎn)品介紹Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.

    Function:
    Forms calcium-sensitive chloride channels. Permeable to bicarbonate.

    Subcellular Location:
    Cell membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Predominantly found in colon and the weakly in fetal brain, spinal cord, retina, lung, trachea, testis and placenta.

    Similarity:
    Belongs to the bestrophin family.

    SWISS:
    Q9C0D5

    Gene ID:
    266675

    Database links:
    Entrez Gene: 510542 Cow
    Entrez Gene: 482521 Dog
    Entrez Gene: 100052813 Horse
    Entrez Gene: 266675 Human
    Entrez Gene: 100345949 Rabbit
    Entrez Gene: 689103 Rat
    Omim: 607336 Human
    SwissProt: Q8NFU0 Human
    Unigene: 302513 Human
    Unigene: 84672 Rat


    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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